ISBN-10:
0387262873
ISBN-13:
9780387262871
Pub. Date:
05/04/2006
Publisher:
Springer US
Computational and Statistical Approaches to Genomics / Edition 2

Computational and Statistical Approaches to Genomics / Edition 2

by Wei Zhang, Ilya ShmulevichWei Zhang

Hardcover

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Overview

The second edition of this book adds eight new contributors to reflect a modern cutting edge approach to genomics. It contains the newest research results on genomic analysis and modeling using state-of-the-art methods from engineering, statistics, and genomics. These tools and models are then applied to real biological and clinical problems. The book’s original seventeen chapters are also updated to provide new initiatives and directions.

Product Details

ISBN-13: 9780387262871
Publisher: Springer US
Publication date: 05/04/2006
Edition description: 2nd ed. 2006
Pages: 416
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

Microarray Image Analysis and Gene Expression Ratio Statistics.- Statistical Considerations in the Assessment of cDNA Microarray Data Obtained Using Amplification.- Sources of Variation in Microarray Experiments.- Studentizing Microarray Data.- Exploratory Clustering of Gene Expression Profiles of Mutated Yeast Strains.- Selecting Informative Genes for Cancer Classification Using Gene Expression Data.- Finding Functional Structures in Glioma Gene-Expressions Using Gene Shaving Clustering and MDL Principle.- Design Issues and Comparison of Methods for Microarray-Based Classification.- Analyzing Protein Sequences Using Signal Analysis Techniques.- Statistical Methods in Serial Analysis of Gene Expression (SAGE).- Normalized Maximum Likelihood Models for Boolean Regression with Application to Prediction and Classification in Genomics.- Inference of Genetic Regulatory Networks.- Regularization and Noise Injection for Improving Genetic Network Models.- Parallel Computation and Visualization Tools for Codetermination Analysis of Multivariate Gene Expression Relations.- Single Nucleotide Polymorphisms and their Applications.- The Contribution of Alternative Transcription and Alternative Splicing to the Complexity of Mammalian Transcriptomes.- Computational Imaging, and Statistical Analysis of Tissue Microarrays.

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