Concepts in Pharmacogenomics

Concepts in Pharmacogenomics

by Martin M. Zdanowicz

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Product Details

ISBN-13: 9781585285167
Publisher: American Society of Health-System Pharmacists
Publication date: 06/01/2017
Edition description: New Edition
Product dimensions: 0.00(w) x 0.00(h) x 0.00(d)

About the Author


Dr. Zdanowicz received an M.A. in biology from S.U.N.Y Binghamton in 1985 and completed his Ph.D. in Pharmacology at St. John’s University in 1992. After completing his doctorate, he went on to work as a research scientist at North Shore University Hospital-Cornell Medical College in the area of endocrinology & metabolism until 1996. He took a full time faculty appointment with the Massachusetts College of Pharmacy & Health Sciences in 1996. He was promoted to associate professor in 2000. Dr. Zdanowicz received the Trustee’s Awarded for teaching excellence in 2000 and was Pharmacy teacher of the year at the Massachusetts College of Pharmacy & Health Sciences in 2001. His teaching areas included pharmacology, pathophysiology, and biochemistry. Dr. Zdanowicz served as chair of Pharmaceutical Sciences and Director of Graduate Studies from 2002-2004.
Dr. Zdanowicz is currently on faculty at South University School of Pharmacy in Savannah, Georgia where he was voted the Pharmacy Teacher of the Year in 2004, 2006 and 2007. He was promoted to full professor in January of 2008. He currently serves as chair of the School of Pharmacy Assessment Committee, Awards & Scholarship Committee and Promotion Committee. His current research interests include pharmacogenomics, pharmacy curriculum development and pharmacy education. Dr. Zdanowicz currently holds membership in numerous professional societies and has published more than 35 articles and two textbooks.

Table of Contents

TABLE OF CONTENTS  
Preface .........................................................................................................................................................................................iv
Contributors .............................................................................................................................................................................vi
Reviewers ...................................................................................................................................................................................vii
Part I—Fundamentals of Pharmacogenomics........................................................................................................................1
Chapter 1: Pharmacogenomics: Past, Present, and Future............................................................................3
Martin M. Zdanowicz, Ph.D., MA
Chapter 2: The Genetic Basis of Pharmacogenomics...................................................................................19
Taimour Y. Langaee, MSPH, Ph.D.; Jaekyu Shin, Pharm.D., MS, BCPS
Chapter 3: Methodologies in Pharmacogenomics.........................................................................................55
Christina L. Aquilante, Pharm.D.
Chapter 4: The Pharmacogenetics of Drug Metabolism..............................................................................85
G. Scott Weston, R.Ph., Ph.D.
Chapter 5: Pharmacogenomics and Drug Transport/Efflux.......................................................................129
Arthur G. Cox, Ph.D.
Chapter 6: Pharmacodynamics and Pharmacogenomics...........................................................................155
Kathy D. Webster, Pharm.D., Ph.D.
Part II—Applications of Pharmacogenomics in Therapeutics.......................................................................................181
Chapter 7: Cardiovascular Disease...................................................................................................................183
Kathryn M. Momary, Pharm.D., BCPS; Michael A. Crouch, Pharm.D., FASHP, BCPS
Chapter 8: Hematology/Oncology Pharmacogenomics..............................................................................213
Todd A. Thompson, Ph.D.
Chapter 9: Central Nervous System.................................................................................................................237
Megan Jo Ehret, Pharm.D., BCPP
Chapter 10: Infectious Diseases.........................................................................................................................275
Tawanda Gumbo, MD; John D. Cleary, Pharm.D., FCCP
Chapter 11: Respiratory Diseases ......................................................................................................................291
Emily Weidman-Evans, Pharm.D., AE-C, CPE; W. Greg Leader, Pharm.D.
Chapter 12: Toxicogenomics...............................................................................................................................321
Helen E. Smith, MS, Ph.D., R.Ph.
Part III: Important Issues in Pharmacogenomics............................................................................................................339
Chapter 13: The Role of Pharmacists in Pharmacogenomics.....................................................................341
Ajoy Koomer, Ph.D., MS, E.M.B.A.; Miriam A. Ansong, Pharm.D.
Chapter 14: Pharmacogenomics and Clinical Testing...................................................................................351
James W. Fetterman, Jr., Pharm.D.; Pamela F. Hite, Pharm.D.
Chapter 15: Pharmacogenomics in Pharmacy Education............................................................................363
Ajoy Koomer, Ph.D., MS, E.M.B.A.
Chapter 16: Ethical Considerations in Pharmacogenomics........................................................................375
Sally A. Huston, Ph.D.
Chapter 17: Future Promise of Pharmacogenomics in Clinical Practice.................................................399
Jeffery D. Evans, Pharm.D.
Index ................................................................................................................................................................................409  

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