This book provides comprehensive insights into congenital heart disease from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. It is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and related animal models and pathways. Taken together these chapters, which were written by and for clinicians and researchers, provide an integrated and cutting-edge resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.
|Edition description:||1st ed. 2016|
|Product dimensions:||6.10(w) x 9.25(h) x (d)|
About the Author
Silke Rickert Sperling, Phd, is Professor at the Experimental and Clinical Research Center Charité, Medical University Berlin and Group leader of the Cardiovascular Genetics Group. She is Professor for Biology, Chemistry and Pharmacy at the Free University Berlin. Her research focuses on elucidating the molecular mechanisms as well as genetic parameters underlying cardiac development in health and disease.
Robert Kelly, PhD, is Group Leader at the Developmental Biology Institute of Marseilles – Luminy in France. His groupś research focuses on the cellular and molecular processes regulating development of these progenitor cells in the mouse and their contribution to the developing heart and craniofacial skeletal muscles.
Table of ContentsSection I: General introduction in cardiac development.- Section II: Different chapters covering the different types of congenital heart disease.- Section III: The overall perspective.
What People are Saying About This
“I am very glad that I came across your book "Congenital heart diseases: The Broken Heart" which has become very handy to look into the details of the developmental aspect of different heart diseases with animal models. I bought an electronic book, which I really like. Thank you for bringing out this book. I believe this will help young generation of pediatric cardiologists and researchers to understand the genetic/biological mechanisms of these disorders.” (Laxmi Ghimire, MD, Clinical Fellow, PGY5, Pediatric Cardiology, UCSF Benioff Children's Hospital, San Francisco, CA)