Pub. Date:
Springer-Verlag New York, LLC
Connexins: A Guide / Edition 1

Connexins: A Guide / Edition 1

by Andrew Harris, Darren Locke


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Product Details

ISBN-13: 9781934115466
Publisher: Springer-Verlag New York, LLC
Publication date: 12/22/2008
Edition description: 2009
Pages: 573
Product dimensions: 6.20(w) x 9.30(h) x 1.30(d)

Table of Contents

Editor's Note v

Contributors xi

Part I Fundamentals of Connexin Biology 1

1 The Family of Connexin Genes Eric C. Beyer Viviana M. Berthoud 3

2 Gap Junction Channel Structure Mark Yeager 27

3 The Connexin Channel Pore: Pore-Lining Segments and Residues Vytas K. Verselis 77

4 Voltage-Gating Mechanisms of Connexin Channels Thaddeus Bargiello Peter Brink 103

5 Chemical Gating of Connexin Channels Rebecca Lewandowski Junko Shibayama Eva M. Oxford Rosy Joshi-Mukherjee Wanda Coombs Paul L. Sorgen Steven M. Taffet Mario Delmar 129

6 Electrical Signaling with Neuronal Gap Junctions Barry W. Connors 143

7 Permeability of Connexin Channels Andrew L. Harris Darren Locke 165

8 Pharmacology of Connexin Channels Miduturu Srinivas 207

9 Biogenesis and Degradation of Gap Junctions Linda S. Musil 225

10 Gap Junction Morphology and Dynamics in Situ Gina E. Sosinsky Guido M. Gaietta Ben N.G. Giepmans 241

11 Biochemistry of Connexins Joell L. Solan Paul D. Lampe 263

12 Pannexins or Connexins? Gerhard Dahl Andrew L. Harris 287

Part II Connexins in Organ Systems and Processes 303

13 Foreword: Gap Junctions and Emergent Organ Properties Daniel Goodenough 305

14 Connexins in Skin Biology Trond Aasen David P. Kelsell 307

15 Connexins in the Nervous System Charles K. Abrams John E. Rash 323

16 Connexins in the Respiratory Epithelium Bernard Foglia Isabelle Scerri Tecla Dudez Marc Chanson 359

17 Connexins in Skeletal Biology Roberto Civitelli Henry J. Donahue 371

18 Connexins in Lens Development and Disease Teresa I. Shakespeare Richard T. Mathias Thomas W. White 387

19 Connexins in the Mammalian Retina Stephen C. Massey 397

20 Connexins in the Inner Ear ReginaNickel Andrew Forge Daniel Jagger 419

21 Connexins in the Heart Nicholas J. Severs 435

22 Connexins in the Vasculature Cor de Wit Stephanie E. Wolfle 457

23 Connexins and Atherosclerosis Anna Pfenniger Isabelle Roth Brenda R. Kwak 469

24 Connexins in the Female Reproductive System Gerald M. Kidder Elke Winterhager 481

25 Connexins in the Male Reproductive System Georges Pointis Celine Fiorini Jerome Gilleron Diane Carette Dominique Segretain 495

26 Connexins and Secretion Sabine Bavamian Philippe Klee Florent Allagnat Jacques-Antoine Haefliger Paolo Meda 511

27 Connexins and Carcinogenesis Sophie Crespin Norah Defamie Laurent Cronier Marc Mesnil 529

Appendix Toward a New Nomenclature for Connexin Genes Gerald M. Kidder 543

Index 547

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