Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach

Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach

by Daniel C. Baumgart (Editor)

Paperback(Softcover reprint of the original 2nd ed. 2017)

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Product Details

ISBN-13: 9783319815770
Publisher: Springer International Publishing
Publication date: 06/18/2018
Edition description: Softcover reprint of the original 2nd ed. 2017
Pages: 695
Product dimensions: 8.27(w) x 10.98(h) x (d)

About the Author

Daniel C. Baumgart, MD

Inflammatory Bowel Disease Center

Department of Gastroenterology and Hepatology

Charité Medical Center--Virchow Hospital

Medical School of the Humboldt University of Berlin


Table of Contents

Part 1 Epidemiology

Chapter 1 Environmental Factors in the Epidemiology of Inflammatory Bowel Disease
Morten H. Vatn

Part 2 Immunobiology

Chapter 2 The Intestinal Immune System in Health
Per Brandtzaeg

Chapter 3 Understanding the Epithelial Barrier in Inflammatory Bowel Disease
Matthew A. Odenwald, Jerrold R. Turner

Chapter 4 Intestinal Microbiology and Ecology in Crohn's Disease and Ulcerative Colitis
Dirk Haller, Ludovica F. Butto

Chapter 5 The Immune System in Inflammatory Bowel Disease: Antimicrobial Peptides
Charles L. Bevins

Chapter 6 Vascular Responses to Intestinal Inflammation
D. Neil Granger, Norman R. Harris

Chapter 7 Immunobiology of Human Dendritic Cells in Inflammatory Bowel Disease
Daniel C. Baumgart

Chapter 8 Immunobiology of T-Cells in Inflammatory Bowel Disease
S. Snapper, D. Nguyen, A Biswas

Chapter 9 Immunobiology of B cells in Inflammatory Bowel Disease
Atsushi Mizoguchi, Atul K. Bhan

Chapter 10 Immune Cells: Monocytes and Macrophages
Gerhard Rogler

Chapter 11 Immune Functions of Epithelial Cells in Inflammatory Bowel Disease
Eric L. Campbell, Sean P. Colgan

Chapter 12 Autophagy and Endoplasmic Reticulum Stress
Arthur Kaser

Chapter 13 Matrix Metalloproteinases
Paolo Biancheri, Thomas T. MacDonald

Chapter 14 Paradigm of T-cell Differentiation in Inflammatory Bowel Disease
Takashi Nagaishi, Mamoru Watanabe

Chapter 15 Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal Inflammation
Cynthia Reinoso Webb, Matthew B. Grisham

Chapter 16 Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel Disease
Jorge O. Múnera, James M. Wells

Part 3 Diagnostic Approach

Chapter 17 Enhanced Endoscopy
Ralf Kiesslich

Chapter 18 Magnetic Resonance Enterography
Patrik Rogalla, Luis Guimaraes

Chapter 19 Computed Tomography Enterography and Inflammatory Bowel Disease
J. G. Fletcher

Chapter 20 Ultrasound in Inflammatory Bowel Disease
A. Potthoff, C. Agné, M. Gebel

Chapter 21 Laboratory Evaluation, Including Novel Diagnostic Markers
M. Flamant, X. Roblin

Chapter 22 Pathology of Inflammatory Bowel Disease
Nora E. Joseph, Christopher R. Weber

Chapter 23 Objective Assessment of Clinical Disease Activity
Edouard Louis, Catherine Van Kemseke, Catherine Reenaers

Chapter 24 Objective Assessment of Endoscopic Disease Activity and Mucosal Healing
Britt Christensen, David T. Rubin

Chapter 25 Evaluation of Quality of Life in Crohn's disease and Ulcerative Colitis: What Is Health-Related Quality of Life?
Katrine Carlsen, Pia Munkholm, Johan Burisch

Chapter 26 Evaluation of Health Economics in Inflammatory Bowel Disease
Reena Khanna, Brian G. Feagan

Part 4 Therapy Crohn’s Disease

Chapter 27 The Natural History of Inflammatory Bowel Disease
Charles N. Bernstein

Chapter 28 Conventional Medica Management of Crohn's Disease: Sulfasalazine
Miquel A. Gassull, Eduard Cabré

Chapter 29 Steroid Therapy for Crohn's Disease
A. Hillary Steinhart

Chapter 30 Thiopurines in Crohns' disease
Adi Lahat, Rami Eliakim

Chapter 31 Conventional Medical Management of Crohn's Disease: Methotrexate
Grace Harkin, Laurence Egan

Chapter 32 Adalimumab for the Treatment of Crohn’s Disease
Remo Panaccione

Chapter 33 Biologic Therapy of Crohn's Disease: Certolizumab
Alessandro Armuzzi, Daniela Pugliese

Chapter 34 Biologic Therapy of Crohn's Disease: Infliximab
Jan-Michael A. Klapproth, Gary R. Lichtenstein

Chapter 35 Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease Treatment
Peter J. Mannon

Chapter 36 Biologic Therapy of Crohn's Disease: Natalizumab, Vedolizumab and anti-MadCAM
Pieter Hindryckx, Geert D’Haens

Chapter 37 Optimal Management of Fistulizing Crohn's Disease
Bruce Sands, Farhad Peerani

Part 5 Therapy Ulcerative Colitis

Chapter 38 Sulfasalazine and 5-Aminosalicylates for Ulcerative Colitis
Reena Khanna, John K. Marshall

Chapter 39 Conventional Therapy of Ulcerative Colitis: Corticosteroids
Kirstin Taylor, Peter R. Gibson

Chapter 40 Medical Management of Ulcerative Colitis: Conventional Therapy--Azathioprine
Barrett G. Levesque, Edward V. Loftus

Chapter 41 Calcineurin Inhibitors in Ulcerative Colitis
Andreas Fischer, Daniel C. Baumgart

Chapter 42 Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: Infliximab
Mindy Lam, Brian Bressler

Chapter 43 Biologic Therapy of Ulcerative Colitis: Adalimumab
Walter Reinisch

Chapter 44 Biologic Therapy of Ulcerative Colitis: Golimumab
Mark A. Samaan, Peter M. Irving

Chapter 45 Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAM
Severine Vermeire

Chapter 46 Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel Disease
Paolo Gionchetti, Carlo Calabrese, Andrea Calafiore, Fernando Rizzello

Chapter 47 Biosimiliars in the Treatment of Inflammatory Bowel Disease
Vivian W. Huang, Richard N. Fedorak

Chapter 48 Step-up vs. Top-down Approach in Crohn’s Disease
Christine Y. Yu, Daniel W. Hommes

Chapter 49 Leucocytapheresis Therapy of Inflammatory Bowel Disease
Takanori Kanai

Chapter 50 Surgical Management of Crohn's Disease and Ulcerative Colitis
Robert R. Cima, John H. Pemberton

Part 6 Extraintestinal Manifestations

Chapter 51 Extraintestinal Manifestations: Autoimmune Hepatitis
Michael Manns, Nora Schweitzer

Chapter 52 Primary Sclerosing Cholangitis
Roger W. Chapman, Kate D. Williamson

Chapter 53 Autoimmune Pancreatitis and Other Organ Involvement
Go Kuwata, Terumi Kamisawa

Chapter 54 Cutaneous and Oral Manifestations of Inflammatory Bowel Disease
Caroline P. Allen, Susan M. Burge

Chapter 55 Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel Disease
Alistair Tindell, Hanna Johnsson, Iain B. McInnes

Part 7 Nutrition

Chapter 56 Nutrition in Inflammatory Bowel Disease
Alan L. Buchman

Part 8 Pregnancy, Family Planning and Pediatric Aspects

Chapter 57 Pregnancy and Fertility in Inflammatory Bowel Disease
Rebecca Matro, Uma Mahadevan

Chapter 58 Pediatric Aspects of Inflammatory Bowel Disease
Brendan Boyle, Jeffrey S. Hyams

Part 9 Surveillance and Prevention

Chapter 59 Management and Prevention of Infectious Diseases in Irritable Bowel Disease Patients
Kristine Macartney, Nigel Crawford

Chapter 60 Incidence of Cancer and Screening in Inflammatory Bowel Disease
Jimmy K. Limdi, Francis A. Farraye

Chapter 61 Inflammatory Bowel Diseases: How to Identify High Risk Patients
Jacques Cosnes, Harry Sokol

Part 10 Patient Perspective and Resources

Chapter 62 Patient Perspective on Inflammatory Bowel Disease
Ayesha Williams, Marjorie Merrick

Chapter 63 Patient Resources in Inflammatory Bowel Disease
Sanna Lönnfors, Marco Greco

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