ISBN-10:
1259835316
ISBN-13:
9781259835315
Pub. Date:
02/15/2019
Publisher:
McGraw-Hill Professional Publishing
CURRENT Diagnosis & Treatment Neurology, Third Edition / Edition 3

CURRENT Diagnosis & Treatment Neurology, Third Edition / Edition 3

by John C. M. Brust
Current price is , Original price is $99.0. You

Temporarily Out of Stock Online

Please check back later for updated availability.

Overview

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.


Practical, up-to-date strategies for assessing and managing the neurologic conditions most frequently seen in adults and children

•Introductory chapters address specific symptoms and diagnostic procedures; subsequent chapters are disease specific and adhere to a standard format, beginning with Essentials of Diagnosis, followed by Clinical Findings, Differential Diagnosis, Treatment, and Prognosis
•Coverage of disorders in both adults and children
•Thorough coverage of diagnostic tests and the very latest pharmacologic treatments
•Practical information on common conditions such as headaches, movement disorders, and central nervous system infections
•Valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic
•Expert help with ischemic and hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, and more
•Each chapter written by experts in that area, without losing readability or coherence

Product Details

ISBN-13: 9781259835315
Publisher: McGraw-Hill Professional Publishing
Publication date: 02/15/2019
Edition description: 3rd ed.
Pages: 624
Sales rank: 626,522
Product dimensions: 7.30(w) x 9.00(h) x 1.10(d)

About the Author

John C. Brust, MD is Professor of Clinical Neurology, Department of Neurology, The Neurological Institute of New York, Columbia Medical Center.

Table of Contents

Authors ix

Preface xiii

Section 1 Neurologic Investigations

1 Electroencephalography Tina Shih, MD 1

General Considerations 1

When to Order 1

Findings 1

Continuous EEG Monitoring 3

2 Electromyography, Nerve Conduction Studies, & Evoked Potentials Dora Leung, MD 4

Electromyography & Nerve Conduction Studies 4

Nerve Conduction Studies 4

Needle Electromyography 8

Single-Fiber Electromyography 11

Evoked Potentials 12

Visual Evoked Potentials 12

Brainstem Auditory Evoked Potentials 12

Somatosensory Evoked Potentials 12

3 Neuroradsology Maria J. Borja, MD John P Loh, MD 14

Plain Films 14

Computed Tomography 14

Magnetic Resonance Imaging 17

Advanced Magnetic Resonance Imaging Techniques 24

Myelography & Postmyelography Computed Tomography 24

Catheter Angiography 26

Interventional Neuroradiology 27

Ultrasonography 27

Nuclear Medicine 29

Section II Neurologic Disorders

4 Coma John CM. Brust, MD 31

General Considerations 31

Pathogenesis 31

Clinical Findings 31

Differential Diagnosis 33

5 Aphasia, Apraxia, & Agnosia John C.M. Brust MD 37

Aphasia 37

Apraxia 39

Agnosia 40

6 Hearing Loss & Dizziness Jack J. Wazen, MD, FACS Soha N. Ghossaini, MD, FACS Benjamin J. Wycheriy, MD 41

Hearing Loss 41

Tinnitus 43

Dizziness 44

7 Epilepsy & Seizures Tina Shih, MD 50

Incidence & Pathogenesis 50

Seizure Types 50

Epilepsy Syndromes 55

Clinical Findings 57

Differential Diagnosis 59

Treatment 60

Prognosis 65

8 Headache & Facial Fain Mark W. Green, MD, FAAN Anna Pace, MD 66

Approach to the Patient with Headache 66

Primary Headache Syndromes 66

Migraine 66

Tension-Type Headache 72

Trigeminal Autonomic Cephalgias 73

Other important Headache Syndromes 75

Medication Overuse Headache 75

New Daily Persistent Headache 75

Secondary Headaches 76

Meningitis 76

Sinus Headache 76

Ocular Causes of Headache 76

Hypertension 76

Subarachnoid Hemorrhage 76

Brain Tumor 77

Cerebral Venous Sinus Thrombosis 77

Idiopathic Intracranial Hypertension 77

Intracranial Hypotension 77

Giant Cell Arteritis 77

Exertional Headache 78

Sexually Induced Headache 78

Cardiac Cephalalgia 78

Carotid or Vertebral Artery Dissection & Carotidynia 78

Cold Stimulus Headache 78

Headaches Associated with Sleep 79

Pain in the Face, Pharynx, Joint, & Ear 79

Trigeminal Neuralgia 79

Glossopharyngeal Neuralgia 80

Yawning Headache 80

Eagle Syndrome 80

Red Ear Syndrome 80

Temporomandibular Joint Disorder 81

Primary Stabbing Headache 81

Nummular Headache 81

9 Dementia & Memory Loss Karen Marder, MD, MPH Lawrence 5. Honig, MD, PhD William C. Kreisl, MD, Nikolaos Scarmeas, MD, MS Chen Zhao, MD Edward Huey, MD Juliana R. Dutra, MD James M. Noble, MD, MS Clinton B. Wright, MD, MPH 82

Alzheimer Disease 82

Mild Cognitive Impairment 89

Vascular Cognitive Impairment 90

Frontotemporal Dementias 92

Progressive Supranuclear Palsy 95

Corticobasal Degeneration 97

Parkinson Disease Dementia 99

Dementia with Lewy Bodies 101

Normal Pressure Hydrocephalus 103

Transient Global Amnesia 105

Huntington Disease 107

10 Cerebrovascular Disease: Ischemic Stroke & Transient Ischemic Attack Joshua Z. Willey, MD 109

General Considerations 109

Pathogenesis 109

Clinical Findings 110

Acute Ischemic Stroke Treatment 113

Prevention 117

Prognosis & Rehabilitation 119

11 Cerebrovascular Disease: Hemorrhagic Stroke Richard A. Bernstein, MD, PhD Philip Chang, MD 120

Intraparenchymal Hemorrhage 120

Subarachnoid Hemorrhage 131

Aneurysmal Subarachnoid Hemorrhage 131

Unruptured Intracranial Aneurysms 139

Infected (Mycotic) Aneurysms 139

Vascular Anomalies 140

Arteriovenous Malformations 140

Cavernous Malformations 141

Dural Arteriovenous Fistulas 142

Vein of Galen Aneurysm 142

Developmental Venous Anomalies 142

Capillary Telangiectasias 143

12 Central Nervous System Neoplasms Christopher E. Mandigo, MD Jeffrey N. Bruce, MD 144

Brain Tumors 144

Primary Brain Tumors 144

Metastatic Tumors 156

Tumors of the Skull 158

Spinal Cord Tumors 159

13 Paraneoplastic Neurologic Syndromes Ugonma N. Chukwueke, MD Alfredo D. Voioschin, MD Andrew B. Lassman, MD Lakshmi Nayak, MD 161

Paraneoplastic Cerebellar Degeneration 164

Paraneoplastic Encephalomyelitis and Encephalitis 165

Paraneoplastic Opsoclonus-Myoclonus 167

Paraneoplastic Myelitis 169

Paraneoplastic Motor Neuron Disease 169

Stiff Person Syndrome 170

Paraneoplastic Visual Syndromes 171

Peripheral Nerve Hyperexcitability 172

Paraneoplastic Peripheral Neuropathy 172

Paraneoplastic Syndromes of the Neuromuscular Junction 173

Dermatomyositis & Polymyositis 174

Acknowledgments 174

14 Trauma Katja E. Wartenberg, MD, PhD Stephan A. Mayer, MD 175

Head Trauma 175

Spinal Trauma 192

15 Movement Disorders Blair Ford, MD Howard Geyer, MD, PhD Susan B. Bressman, MD 199

Parkinsonism & Parkinson Disease 199

Atypical Parkinsonian Syndromes 207

Progressive Supranuclear Palsy 207

Corticobasal Degeneration 208

Multiple System Atrophy 209

Essential Tremor 209

Dystonia 211

Myoclonus 217

Tourette Syndrome & Tic Disorders 219

Tardive Dyskinesia & Other Drug-Related Movement Disorders 222

Acute Syndromes Caused by Neuroleptics 223

Neuroleptic-Induced Parkinsonism 224

Tardive Syndromes 224

Neuroleptic Malignant Syndrome 226

Restless Legs Syndrome 227

16 Ataxia & Cerebellar Disease Harini Sarva, MD Claire Henchcliffe, MD, DPhil 229

Approach to the Ataxic Patient 229

Acquired Ataxias 232

Cerebellar Ischemic Stroke Syndromes 232

Cerebellar Hemorrhage 233

Toxins & Nutritional Deficiencies 233

Abnormal Homeostasis & Ataxia 234

Endocrine Disease & Ataxia 234

Cerebellar Neoplasms 234

Infectious Causes of Ataxia 234

Ataxia Associated with Inflammatory & Autoimmune Disease 234

Gluten Ataxia 235

Ataxia of Paraneoplastic Origin 235

Multiple System Atrophy (Type C) 236

Inherited Ataxias 237

Autosomal Dominant Cerebellar Ataxias 237

Autosomal Recessive Cerebellar Ataxias 242

Cerebellar Ataxia in Mitochondrial Disorders 246

X-Linked Ataxias: Fragile X-Associated Tremor & Ataxia Syndrome 248

17 Multiple Sclerosis & Demyelinating Diseases Bruce A.C. Cree, MD, PhD, MAS 250

Multiple Sclerosis 250

Acute Transverse Myelitis 271

Neuromyelitis Optica Spectrum Disorder 273

Acute Disseminated Encephalomyelitis 275

Antimyelin Oligodendrocyte Glycoprotein Demyelination 276

Chronic Relapsing Inflammatory Optic Neuropathy 276

18 Nontraumatic Disorders of the Spinal Cord Olajide Williams, MD, MSc Jared Levin, MD Michelle Stern, MD 278

Spinal Cord Syndromes 278

Spinal Cord Tumors 280

Myelitis 280

Spinal Epidural Abscess 281

Syringomyelia 283

Spinal Cord Arteriovenous Shunts 284

Spinal Cord Infarction 285

Spinal Epidural & Subdural Hematomas 286

Subacute Combined Degeneration 287

Amyotrophic Lateral Sclerosis & Other Motor Neuron Diseases 287

Spinocerebellar Degeneration 287

Radiculopathy 287

Lumbar Stenosis 292

Cervical Spondylotic Myelopathy 293

Issues in Rehabilitation of Spinal Cord-Injured Patients 294

Bladder Dysfunction 294

Bowel Dysfunction 294

Pressure Sores 295

Spasticity 295

Autonomic Dysfunction 295

Contractures 296

Sexual Dysfunction After Spinal Cord Injury 296

Deep Vein Thrombosis 296

19 Peripheral Neuropathies Thomas H. Brannagan III, MD 297

Mononeuropathies 299

Cranial Nerve Disorders 299

Upper Extremity Nerves 306

Lower Extremity Nerves 312

Multiple Mononeuropathy Syndromes 317

Acquired Polyneuropathies 318

Autoimmune Neuropathies 318

Infectious Polyneuropathy 325

Toxic & Metabolic Neuropathies 328

Neuropathies Associated with 330

Systemic Disease 330

Hereditary Peripheral Neuropathies 334

20 Motor Neuron Diseases Neil A. Shneider, MD, PhD Michio Hirano, MD 340

Amyotrophic Lateral Sclerosis 344

Lower Motor Neuron Disorders 349

Spinal Muscular Atrophy 349

Monomelic Amyotrophic Lateral Sclerosis 349

Kennedy Disease 350

Upper Motor Neuron Disorders 350

Hereditary Spastic Paraparesis 350

Primary Lateral Sclerosis 350

21 Autonomic Disorders Louis H. Weimer, MD, FAAN, FANA 352

Dysautonomia 352

Treatment of Orthostatic Hypotension 354

Disorders Associated with Autonomic Failure 355

Neurodegenerative Disorders & Parkinsonian Syndromes 355

Acute & Subacute Autonomic Neuropathies 356

Chronic Autonomic Neuropathies 358

Orthostatic Intolerance & Postural Orthostatic Tachycardia Syndrome 360

Sudomotor (Sweating) Disorders 361

Autonomic Symptoms in Spinal Cord Injury 362

22 Myasthenia & Other Disorders of the Neuromuscular Junction Svetlana Faktorovich, MD Shanna K, Patterson, MD 363

Neuromuscular Transmission 363

Myasthenia Gravis (Autoimmune Myasthenia) 363

Congenital Myasthenia Syndromes 371

Lambert-Eaton Myasthenic Syndrome 371

Botulism 373

Tick Paralysis 374

23 Diseases of Muscle Christina M. Ulane, MD, PhD Olajide Williams, MD 375

Myopathy 375

Acquired Myopathies 377

Inflammatory Myopathies 377

Infectious Myopathies 382

Drug-Induced or Toxic Myopathies 384

Corticosteroid Myopathy 384

Cholesterol-Lowering Agent Myopathy 385

Alcoholic Myopathy 386

Myopathy in Critical Illness 387

Secondary Metabolic & Endocrine Myopathies 387

Hypokalemic Myopathy 387

Hypophosphatemic Myopathy 387

Chronic Renal Failure-Related Myopathies 388

Diabetic Muscle Infarction 388

Hypothyroid Myopathy 388

Hyperthyroid Myopathy 388

Hyperparathyroid Myopathy 389

Vitamin D-Related Myopathy 389

Cushing Disease 389

Primary Metabolic Myopathies 389

Mitochondrial Myopathies 391

Myoglobinuria 391

Channelopathies 391

Congenital Myopathies 392

Muscular Dystrophies 392

Congenital Muscular Dystrophies 392

Duchenne Muscular Dystrophy 392

Becker Muscular Dystrophy 394

Myotonic Dystrophy 395

Fascioscapulohumeral Dystrophy 396

Limb-Girdle Muscular Dystrophy 397

Emery-Dreifuss Muscular Dystrophy 397

Oculopharyngeal Muscular Dystrophy 398

24 Mitochondrial Diseases Michio Hirano, MD 399

Mitochondrial DNA Mutations 400

Kearns-Sayre Syndrome & Chronic Progressive External Ophthalmoplegia 400

Melas Syndrome 402

Merrf Syndrome 403

Narp Syndrome & Maternally inherited Leigh Syndrome 403

Leber Hereditary Optic Neuropathy 404

Nuclear DNA Mutations 405

Other Mitochondrial Disorders 406

Nucleoside Reverse-Transcriptase Inhibitor-Induced Myopathy 406

Aminoglycoside-Induced Deafness 406

25 Neurologic Intensive Car Santiago Ortega-Gutierrez, MD Alan Z. Segal, MD 408

Increased Intracranial Pressure 408

Hypoxic-Ischemic Encephalopathy After Cardiac Arrest 412

Neuromuscular Weakness in Critical Illness 414

26 Bacterial, Fungal, & Parasitic Infections of the Nervous System Barbara S. Koppel, MD Kiran T. Thakur, MD Adedoyin Akinlonu, MD, MPH 416

Bacterial Infections 416

Bacterial Meningitis 416

Brain Abscess 424

Subdural Empyema 428

Epidural Abscess 429

Intracranial Suppurative Thrombophlebitis 432

Malignant Otitis Externa & Otitis Media 434

Chronic & Recurrent Meningitis 435

Tuberculosis & Other Granulomatous Infections 438

Central Nervous System Tuberculosis 438

Leprosy (Mycobacterium Leprae) 443

Infectious Toxins 443

Tetanus 443

Botulism 444

Diphtheria 444

Fungal Infections 444

Spirochetal Infections 448

Syphilis 448

Nonsexually Transmitted Treponematoses 451

Leptospirosis 451

Lyme Disease (Neuroborreliosis) 452

Rickettsial, Protozoal, & Helminthic Infections 454

Rickettsial & Other Arthropod-Borne Infections 454

Protozoal Infections 457

Helminthic Infections 464

27 Viral Infections of the Nervous System Kiran Thakur, MD James M. Noble, MD, MS 470

Acute Viral Encephalitis 470

Viral Meningitis 475

Viral Central Nervous System Vasculopathies 476

Acute Viral Myelitis 477

Radiculitis & Ganglionitis 479

Chronic Viral Infections 480

Emerging and Reemerging Viral Neurotropic Infections 482

28 HIV Neurology Deanna Saylor, MD, MHS Ned Sacktor, MD Jeffrey Rumbaugh, MD Jeffrey Sevigny, MD Lydia B. Estanislao, MD 484

Central Nervous System Disorders Associated with HIV 484

Cryptococcal Meningitis 484

Toxoplasmosis of the Central Nervous System 486

Primary Central Nervous System Lymphoma 488

Progressive Multifocal Leukoencephalopathy 489

HIV-Associated Neurocognitive Disorder 490

HIV-Associated Myelopathy 492

HIV Meningitis 493

Varicella-Zoster Vasculitis 493

Cytomegalovirus Encephalitis 494

Peripheral Nervous System Complications 494

Cytomegalovirus Polyradiculopathy 494

Distal Symmetric Polyneuropathy 496

Mononeuropathy Multiplex 497

Acute Inflammatory Demyelinating Polyneuropathy 497

HIV-Associated Neuromuscular Weakness Syndrome 498

HIV-Associated Myopathy 498

HIV-Associated Motor Neuron Disease 499

Immune Reconstitution Inflammatory Syndrome 499

29 Prion Diseases Lawrence S. Honig, MD, PhD 501

Creutzfeldt-Jakob Disease 501

Variant Creutzfeldt-Jakob Disease 503

Gerstmann-Sträussler-Scheinker Syndrome 504

Fatal Familial Insomnia 504

Kuru 504

Treatment of Prion Diseases 505

30 Disorders of Cerebrospinal Fluid Dynamics John C.M. Brust, MD 506

Obstructive Hydrocephalus 506

Intracranial Hypotension 508

Idiopathic Intracranial Hypertension 508

31 Sleep Disorders Andrew J. Westwood, MD Carl Bazil, MD, PhD

Sleep Architecture 511

Sleep Testing 511

Insomnia 512

Narcolepsy and idiopathic Hypersomnia 514

Parasomnias 515

Sleep-Related Breathing Disorders 517

Sleep-Related Movement Disorders 518

Circadian Rhythm Disorders 518

32 Systemic & Metabolic Disorders Laura Lennihan, MD Jason Diamond, MD 520

Nutritional Deficiencies 520

Electrolyte Disorders 521

Hyperglycemia & Hypoglycemia 522

Hypertensive Encephalopathy & Posterior Reversible Encephalopathy Syndrome 523

Cardiac Disease 524

Pulmonary Disease 525

Liver Disease 525

Renal Disease 526

Pancreatic Disease 527

Endocrine Disorders 527

Hematologic Disorders 529

Bone & Joint Disorders 530

Neurosarcoidosis 531

Vasculitis & Connective Tissue Disorders 532

Disordered Temperature Regulation 534

Medication-Induced Neurologic Effects 535

Biologic Neurotoxins 539

Neurotoxicity Caused by Heavy Metals & Industrial Compounds 541

33 Alcoholism John C.M. Brust, MD 544

Ethanol Intoxication 544

Ethanol Dependence & Withdrawal 545

Wernicke-Korsakoff Syndrome 546

Other Neurologic Complications of Alcoholism 547

Treatment of Chronic Alcoholism 548

34 Drug Dependence John CM Brush MD 551

Drugs of Dependence 551

Medical & Neurologic Complications of Abused Substances 555

35 Psychiatric Disorders Eric R. Marcus, MD 558

Approach to the Psychiatric Patient 558

Major Psychiatric Illnesses 559

Organic Brain Syndromes 559

Manic-Depressive Illnesses 559

Schizophrenia 562

Anxiety Disorders 563

Chronic Anxiety 563

Panic Attacks 564

Personality Disorders 565

36 Neurologic Disorders of Childhood & Adolescene Claudia A. Chiriboga, MD, MPH Marc C. Patterson, MD, FRACP 566

Neonatal Neurologic Disorders 566

Hypoxic-Ischemic Encephalopathy 566

Intraventricular Hemorrhage 567

Periventricular Leukoencephalomalacia 568

Neonatal Strokes 568

Developmental Disorders 569

Mental Retardation 569

Cerebral Palsy 571

Autistic Disorder & Pervasive Developmental Disorder 572

Learning Disabilities 573

Attention-Deficit/Hyperactivity Disorder 574

Genetic Disorders 577

Chromosomal Disorders 577

Inborn Errors of Metabolism 578

Congenital Brain Anomalies 581

Neurocutaneous Disorders 581

Neurofibromatosis Type 1 581

Neurofibromatosis Type 2 583

Tuberous Sclerosis Complex 583

Sturge-Weber Syndrome 584

Ataxia-Telangiectasia 584

Index 585

Color insert appears between pages 18 and 19.

Customer Reviews

Most Helpful Customer Reviews

See All Customer Reviews