Cushing's Syndrome: Pathophysiology, Diagnosis and Treatment / Edition 1

Cushing's Syndrome: Pathophysiology, Diagnosis and Treatment / Edition 1

by Marcello D. Bronstein
Pub. Date:
Springer-Verlag New York, LLC


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Cushing's Syndrome: Pathophysiology, Diagnosis and Treatment / Edition 1

Cushinǵs syndrome is a relatively rare clinical disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function and growth impairment in children, all of which severely reduce quality of life and life expectancy. Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment reviews the difficulties in distinguishing Cushing’s syndrome from these and other common conditions, such as central obesity, menstrual irregularity and depression. It also provides state-of-the-art information on various strategies to establish the diagnosis of Cushing’s syndrome and the differential diagnosis among its diverse etiologies, as well as therapeutic approaches. Additionally, a range of conditions that represent challenges for the diagnosis and treatment--such as renal failure, pediatric age, cyclic hypercortisolism, and pregnancy--are covered in detail. A valuable resource not only for endocrinologists but also internal medicine physicians, gynecologists, pediatricians, , pituitary surgeons and urologists, Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment provides insights by experts that will help all physicians dealing with Cushinǵs syndrome to expand their knowledge about the condition and provide targeted, comprehensive care.

Product Details

ISBN-13: 9781603274487
Publisher: Springer-Verlag New York, LLC
Publication date: 10/01/2010
Series: Contemporary Endocrinology
Edition description: 2011
Pages: 304
Product dimensions: 7.68(w) x 10.24(h) x 0.03(d)

Table of Contents

Chapter 1: Physiology and Pathophysiology of the HPA axis, by Margareth Castro and Ayrton Custodio Moreira

Chapter 2: Etiologies of Cushinǵs syndrome, by John Newell-Price

Chapter 3: Pathogenesis of corticotropic tumors, by Shlomo Melmed

Chapter 4: Pathogenesis of adrenocortical tumors, by Madson Q. Almeida, Emilia M. Pinto, and Ana Claudia Latronico

Chapter 5: Clinical features of Cushinǵs syndrome, by Oscar Bruno

Chapter 6: Laboratorial diagnosis of Cushinǵs Syndrome: Differential diagnosis with pseudo-Cushinǵs conditions as obesity, alcoholism and depression, by Francesco Cavagnini

Chapter 7: Laboratorial diagnosis of Cushinǵs syndrome: Differential diagnosis among the different causes of ACTH-dependent and ACTH-independent Cushinǵs syndrome, by Antonio M. Lerário and Marcello D.Bronstein

Chapter 8: Imaging for the differential diagnosis of Cushinǵs syndrome: MRI, CT and isotopic scanning, by Wouter de Herder

Chapter 9: Inferior petrosal sampling for the differential diagnosis of ACTH dependent Cushinǵs syndrome, by James W. Findling and Bradley Javorsky

Chapter 10: ACTH-dependent Cushing syndrome: Treatment of Cushinǵs disease
A) Treatment of Cushings Syndrome: Surgical Treatment, by Edward Laws
B) Adrenal-Directed Treatment Options for Cushing’s Disease, by William Young
C) Radiation Therapy and Stereotactic Radiosurgery for Cushing’s Disease, by Jason P Sheehan
D) Medical Management of Cushing’s syndrome, by Peter Trainer

Chapter 11: ACTH-dependent Cushing syndrome: Clinical and diagnostic aspects, and treatment approaches for ectopic Cushinǵs syndrome, by Ashley Grossman

Chapter 12: Revisiting the Nelson’s syndrome: Corticotroph Tumor Progression after bilateral adrenalectomy in Cushing’s disease, by Xavier Bertagna

Chapter 13: ACTH-independent Cushinǵs syndrome: Adrenocortical tumors, by Maria Candida Fragoso, Ana Claudia Latronico and Berenice B. Mendonca

Chapter 14: ACTH-independent Cushinǵs syndrome: Bilateral macronodular hyperplasia, by Andre Lacroix

Chapter 15: ACTH-independent Cushinǵs syndrome: primary pigmented nodular adrenal disease in the context of Carneýs complex, by Constantine A Stratakis

Chapter 16: Glucocorticoid Resistance, by Elisabeth F.C. van Rossum and Steven W. Lamberts

Chapter 17: Post-operative replacement and assessment of HPA axis recovery in Cushing’s syndrome, by John Wass

Chapter 18: Special aspects of Cushinǵs syndrome: Pregnancy, by David Aron

Chapter 19: Special aspects of Cushinǵs syndrome: Childhood, by M. O. Savage

Chapter 20: Special aspects of Cushinǵs syndrome: Cyclic Cushinǵs syndrome, by Franco Mantero

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