Pub. Date:
Springer International Publishing
Cytochrome P450: Structure, Mechanism, and Biochemistry / Edition 4

Cytochrome P450: Structure, Mechanism, and Biochemistry / Edition 4

by Paul R. Ortiz de Montellano


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Product Details

ISBN-13: 9783319121079
Publisher: Springer International Publishing
Publication date: 03/14/2015
Edition description: 4th ed. 2015
Pages: 912
Product dimensions: 7.01(w) x 10.00(h) x 0.07(d)

About the Author

Paul R. Ortiz de Montellano received his PhD in bioorganic chemistry from Harvard University, Cambridge, MA. After postdoctoral work as a North Atlantic Treaty Organization Fellow in Zürich, Switzerland, and a stint with Syntex in Mexico City and Palo Alto, California, he joined the faculty of the University of California in San Francisco, where he is currently Professor, Vice-chair of the Department of Pharmaceutical Chemistry, and Associate Dean for Research of the School of Pharmacy. His research interests center on the structure, mechanism, inhibition, and biochemistry of hemoproteins, including the cytochrome P450 enzymes. He has received the B.B. Brodie Award in Drug Metabolism from the American Society of Pharmacology and Experimental Therapeutics, the R.T. Williams Distinguished Scientific Achievement Award from the International Society for the Study of Xenobiotics, and the Ernest H. Volwiler Research Achievement Award from the American Association of Colleges of Pharmacy.

Table of Contents

.- Volume 1

.- 1 Structures of Cytochrome P450 Enzymes

.- 2 Electron Transfer Partners of Cytochrome P450

.- 3 Activation of Molecular Oxygen in Cytochromes P450

.- 4 Substrate Oxidation by Cytochrome P450 Enzymes

.- 5 Inhibition of Cytochrome P450 Enzymes

.- 6 Microbial Cytochromes P450

.- 7 P450s in Plants, Insects and their Fungal Pathogens

.- 8 P450 Biotechnology

.- Volume 2

.- 9 Human Cytochrome P450 Enzymes

.- 10 Nuclear Receptor-Mediated Regulation of Cytochrome P450 Genes

.- 11 Hormonal Regulation of Liver Cytochrome P450 Enzymes

.- 12 P450 Enzymes in Steroid Processing

.- 13 P450 Enzymes in Lipid Oxidation.

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