The contributions gathered in this volume are the result of the German-French research project HIGEOMES - "The historical geography of Upper Mesopotamia in the 2nd millennium BC: Interdisciplinary research" (ANR/DFG). The first part, "From Aur to Mari," covers the Sinjar, Khabur and Taurus regions, that is, the north of Upper Mesopotamia. The focus lies on spatial phenomena of political structures in the first half of the 2nd millennium BC, based on written sources or archaeological findings (contributions by D. Charpin, M. Guichard, A. Jacquet, C. Nicolle, J.-M. Durand & N. Ziegler). The second part, "Beyond Upper Mesopotamia," considers regions at the borders or even outside of Upper Mesopotamia proper. The city of Akkade remains a point of reference, also in the second millennium. With regard to the ongoing discussion about the localization of the city of Akkade it seemed to make sense to bring the state of research concerning the written sources of the third to the first millennia up to date (contributions by W. Sommerfeld, N. Ziegler, S. Paulus, W. Pethe, L. Marti and R. Pirngruber). The two texts from Tell Sakka are here edited for the first time and analysed as to their importance for a reconstruction of Suppiluliuma I's military campaigns (contributions by F. Abdallah & J.-M. Durand, B. Alexandrov). The third part, "Toponymy and concept of space," consists of essays by I. Arkhipov, E. Cancik-Kirschbaum and N. Ziegler. They treat questions of newly attributed place-names and of the linguistic grasp of large areas and of central structures in Old Babylonian and Middle Assyrian times (libbi matim / libbi mati resp. libbi ali).