The first version was printed at Basel too, in 1543. The publication of De Humani Corporis Fabrica has been a cornerstone in our knowledge of human anatomy, and it remains quoted as such today in all universities around the world. It is also known for the amazing quality and accuracy of its more than 250 illustrations, which include beautiful full pages plates attributed either to famous Italian painter Titian, or to his pupil Calcar, and for the outstanding quality of its printing and typography which was never seen in any other book before 1543.
With regard to these last characteristics, De Humani Corporis Fabrica may also be regarded as the first modern book.
It encompasses the seven following parts, Vesalius introduced as books, all written in Latin:
1: The Bones and Cartilages.
2: The Ligaments and Muscles.
3: The Veins and Arteries.
4: The Nerves.
5: The Organs of Nutrition and Generation.
6: The Heart and Associated Organs.
7: The Brain.
These books are followed by a short Errata post Libri Impressionem, then by a considerable index of 46 pages. The revised edition of De Humani Corporis Fabrica has 877 pages, against 714 for the first, printed in 1543. The original copy that has been used for the printing of this facsimile is one among the best preserved, with no missing page, no tear and no other damage whatsoever. All of its reproduced pages are as clean as those of a recent used book.
One more particularity of this book was the huge cost of its making, which makes it today a very rare piece of historical value whose original printings are currently sold in auctions for sums in excess of one million dollars. There are only 143 known surviving copies of De Humani Corporis Fabrica. That's why this facsimile is a highly desired collectible for any physician.
Vol. I of II: ISBN 978-1503036833
Vol. II of II: ISBN 978-1503061040