ISBN-10:
0387403132
ISBN-13:
9780387403137
Pub. Date:
11/09/2009
Publisher:
Springer New York
Design and Analysis of Vaccine Studies / Edition 1

Design and Analysis of Vaccine Studies / Edition 1

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Product Details

ISBN-13: 9780387403137
Publisher: Springer New York
Publication date: 11/09/2009
Series: Statistics for Biology and Health
Edition description: 2010
Pages: 390
Product dimensions: 6.40(w) x 9.30(h) x 1.20(d)

Table of Contents

Introduction and examples.- Overview of vaccine effects and study designs.- Immunology and early phase trials.- binomial and stochastic transmission models.- R0 and deterministic models.- Evaluating protective effects of vaccination.- Modes of action and time-varying VES.- Further Evaluation of Protective Effects.- Vaccine effects on post-infection outcomes.- House-hold based studies.- Analysis of households in communities.- Analysis of independent households.- Assessing Indirect, total and overall effects.- Randomization and baseline transmission.- Surrogates of protection.

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