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CHAPTER III Facts In The Comparative Development Of The Child (Continued) The changes in the liver are just as marked as those in the heart. During the second month of foetal life, the liver reaches a relatively enormous size; in the third month, the continuation of this growth brings it far into the hypogastric region, and fills the greater part of the abdominal cavity. Through the rest of foetal life, as well as in infancy and childhood, this organ is far greater in size relatively than it later on comes to be. It gradually, in proportion to the rest of the body, becomes smaller and smaller, so that from constituting one-eighteenth of the body weight at birth, it comes to be only one thirty-sixth in the adult. This in itself is sufficiently noteworthy, but looked at in the light of frequent eccentric variations in size, it loses much of its claim to a regular and normal evolution. All that one can say is, that there is a striking difference between the infant and the adult. In the latter the liver ought not to extend beyond the free border of the ribs, and is distinctly confined to theright side of the thorax, while in the former it is pushed down one to two centimetres below the free border of the ribs, and sometimes farther, and it may even invade the left thoracic region as far as to displace both lungs and heart to a considerable extent. In some cases, though without disease, it may grow to a remarkable extent, even so far as to fill up a fair portion of the abdominal space. Likewise, microscopically, there is a tardiness in complete growth, as shown by the arrangement of the liver cells, that is remarkable. In foetal life there are two main sorts of these cells: one is apolyhedral form, much like those of the adult organ; the other is a small round cell that gradu...