Molecular techniques are now being widely applied in clinical pathology laboratories, yet many people working in these facilities have only limited experience of such procedures. Diagnostic Molecular Pathology: A Practical Approach, Volumes I and II bring together a broad spectrum of protocols relevant to the routine molecular analysis of pathological samples. Topics covered in Volume I include those methods which related to morphological analysis, such as immunocytochemistry, in situ hybridization, chromosome analysis, and flow cytometry. Volume II demonstrates additional applications of molecular techniques to clinical samples, including the use of PCR, DNA sequencing, and nucleic acid hybridization for such diverse purposes as pathogen identification and forensic studies. For all the protocols there is expert guidance and detailed instruction on how to ensure accuracy and reliability, which will appeal to people working at all levels in pathology.
Table of Contents
1. Extraction of Nucleic Acids from Clinical Samples and Cultured Cells, V.T-W. Chan