Completely revised and expanded, the 2nd edition of this text brings together all of the latest clinical data and research to comprehensively cover the anatomy, physiology and pathophysiology of the spleen. Provides the latest in spleen related immunology and offers detailed information on the differential diagnosis of diseases involving the spleen. Now includes extensive updates on Hodgkin's disease, malignant lymphomas, leukemias and nonhematopoietic tumors and cysts!
• Describes many lymphoma entities not presented in the previous edition, such as anaplastic large cell lymphoma, splenic marginal zone cell lymphoma, and hepatosplenic T-cell lymphoma. Features extensively updated chapters on myeloproliferative diseases and disorders, disorders of the monocyte macrophage system, vascular lesions, and non-hematopoietic tumours and cysts.
• Classifies disease entities using the latest classification system for lymphomas and myeloid diseases, which integrates molecular, cytogenic, and immunophenotypic data. Illustrates pathologic processes with more than 230 detailed gross and microscopic photographs, including 20 in full colour.
• Emphasizes clinical correlations throughout the text. Reflects the authority of anoutstanding team of editors and contributors, all of whom are experienced hematopathologists.
Table of Contents
SECTION I: GENERAL CONSIDERATIONS. Embryology and Anatomy. Functions of the Spleen. Hypersplenism. Hyposplenism. SECTION II: DISORDERS OF THE WHITE PULP. Non-Neoplastic Proliferations of Splenic Lymphoid Tissue. Granulomatous Disorders. Hodgkins Disease. Malignant Lymphomas. Dysproteinemias and Related Disorders.
SECTION III: DISORDERS OF THE RED PULP. Non-Neoplastic Disorders of Erythrocytes Granulocytes and Platelets. Disorders of the Monocyte-Macrophage System. Leukemias. Myeloproliferative Disorders. Non-Neoplastic Vascular Lesions. Splenic Cysts, Non-Hematopoietic Tumours, and Tumour-like Lesions Splenic Cysts.