Religion in any form has been outlawed and blase hedonism is the norm, in the skewed future of DOLL AND CREATURE. Unleashed into this society of wretched self-absorption is a horrible new drug, Grey Matter, which physically transforms its users into monsters called "Hydes."
With the government unable or unwilling to deal with this threat to its populace, a wealthy Priest/General, himself a veteran of the wars that caused religion to be outlawed, contracts a brilliant scientist to create a prototype "Frankenstein" to deal with the Hyde epidemic. This creature, named Gristle, is formed with only one instinct: to hunt down and mercilessly kill the Hydes and rid society of them.
In a midnight raid against the Hydes, Gristle encounters Doll, a curvaceous beauty branded ugly by the curiously inverted standards of the time. Although able to drive off the maurading horde and save Gristle's "life," Doll is blinded during the Hyde attack. In gratitude, Gristle adapts some Hyde-detection equipment and is able to partially restore Doll's sight.
Together, two outcasts forced into each others lives by chance, DOLL AND CREATURE is a story of a pair of misfits united against a world who fears them and what they represent.