Reviewer: Amy E. Lodolce, PharmD, BCPS (University of Illinois at Chicago College of Pharmacy)
Description: This handbook devoted to providing nutrient depletion/supplementation data is a relatively new addition to the Lexi-Comp collection. The previous edition was published in 1999.
Purpose: The purpose is to provide a quick and concise reference regarding nutrient depletion secondary to medications and information on dietary supplements. This handbook represents the only succinct reference for this topic.
Audience: The book is targeted to healthcare professionals, specifically physicians, nurses, and chiropractors; however, other clinicians including pharmacists and dieticians may find this book valuable. The authors are experienced in health and wellness in addition to pharmacy backgrounds.
Features: The book is composed of several sections including an alphabetical listing of drugs and nutrients and a comprehensive reference section. It is extensively cross-referenced to avoid duplication and facilitate use. The drug section contains a pared down version of the usual Lexi-Comp monograph and includes primarily a list of nutrients depleted and information regarding the strength of the literature. The nutrient portion is more comprehensive and contains information regarding the effect of the nutrient in the body, consequences of deficiency, the recommended daily allowance, a dosing range, and dietary sources for the nutrient. The appendix includes a summary table of nutrient-depletion by drug class, data on herb- and chemotherapy-induced nutrient depletion, and brief information on drug-food interactions. Thereference section deserves to be highlighted because nutrients and dietary supplements are not perceived to be evidence-based. The authors acknowledge this and provide citations and summaries of pertinent articles.
Assessment: This book represents a unique compilation of information. To find similar data, the clinician would have to search various drug and herbal information resources. Notably, it is not intended to be a comprehensive reference, and clinicians should consider looking elsewhere for dosing guidelines and drug interactions. Updated editions are warranted based on the evolving literature and approval of new drugs. Drug information centers, medical libraries, and clinicians with an interest in health and wellness will find this book valuable.