Bill Bixby stars as Dr. David Banner (Bruce Banner in the original comic books), a scientist whose experimentation with gamma rays has a most dramatic effect. Whenever his anger is aroused, Dr. Banner turns into a huge, green, rampaging monstrosity called the Hulk (played by bodybuilder Lou Ferrigno). Unjustly accused of being a criminal in his "Hulk" guise, Dr. Banner is forced to live his life on the fringes of society.