Originally slated for released through Grand National Pictures, Isle of Destiny was redirected to RKO Radio when Grand National folded in late 1939. June Lang stars as Virginia Allerton, a famous aviatrix who crashlands in a remote South Sea Island (a la Amelia Erhardt!) and is promptly kidnapped by gun-runner Barton (Gilbert Roland). Coming to Virginia's rescue are two-fisted US marines Stripes Thornton (William Gargan) and Milly Barnes (Wallace Ford). Also figuring into the storyline are Katherine DeMille as a sultry native with a predilection of disposing of her enemies with poison darts, and septugenarian Etienne Girardot (in his last film appearance) as Barton's semi-comic assistant. Too long by about two reels, Isle of Destiny has the advantage of eye-pleasing Cosmocolor cinematography.