| Jeremy Renner | Gary Webb |
| Paz Vega | Coral Baca |
| Joshua Close | Rich Kline |
| Mary Elizabeth Winstead | Anna Simons |
| Rosemarie DeWitt | Sue Webb |
| Ray Liotta | John Cullen |
| Tim Blake Nelson | Alan Fenster |
| Barry Pepper | Russell Dodson |
| Oliver Platt | Jerry Ceppos |
| Michael Sheen | Fred Weil |
| Michael Kenneth Williams | Ricky Ross |
| Andy Garcia | Norwin Meneses |
| Robert Patrick | Ronald J. Quail |
| Jena Sims | Quail's Girlfriend |
| Robert Pralgo | L.A. Sheriff |
| Hajji Golightly | DEA Agent |
| Ted Huckabee | Bob |
| Lucas Hedges | Ian Webb |
| Matthew Lintz | Eric Webb |
| Parker Douglas | Christine Webb |
| Kai Schmoll | Sacramento Journalist |
| Aaron Farb | Rafael Cornejo |
| Tom Jordan | San Francisco Judge |
| Clay Edmond Kraski | DEA Agent Jones |
| Yul Vázquez | Danilo Blandon |
| Kristen Danch-Powell | Watts Girl |
| Jen Harper | Ricky Ross Trial Judge |
| Manuel Rodriguez | Guard |
| Brett Rice | Hansjorg Baier |
| Jonathan Fritschi | Soldier |
| Gil Bellows | DEA Agent Miller |
| Steve Coulter | Anonymous Agent |
| Kenny Alfonso | Marc Mansfield |
| Dan Futterman | Leo Wolinsky |
| Susan Walters | Los Angeles Times Editor |
| Richard Schiff | Richard Zuckerman |
| David de Vries | Washington Post Editor |
| David Garver | Doug Farah |
| Rhoda Griffis | Female Anchor |
| Andrew Masset | San Jose Mercury News Editor |
| E. Roger Mitchell | Detective |
| Kevin Harrison | Man in Suit |
| Michael H. Cole | Pete |
Technical Credits
| Michael Cuesta | Director |
| Pamela Abdy | Executive Producer |
| Kimberly J. Adams | Costumes/Costume Designer |
| Scott Anderson | Art Director |
| Michael Bederman | Executive Producer |
| Jim Black | Musical Direction/Supervision |
| Sean Bobbitt | Cinematographer |
| Cara Buckley | Executive Producer |
| Luke Crawford | Asst. Director |
| Naomi Despres | Producer |
| Don Handfield | Executive Producer |
| Nathan Johnson | Score Composer |
| Brian A. Kates | Editor |
| Avy Kaufman | Casting |
| Peter Landesman | Executive Producer,Screenwriter |
| Jayme Leach Long | Set Decoration/Design |
| John Paino | Production Designer |
| Jeremy Renner | Producer |
| Aron Siegel | Sound Mixer |
| Scott Stuber | Producer |
| David A. Ticotin | Asst. Director |
| Dennis Towns | Sound Mixer |
| Paul Varrieur | Cinematographer |
