In the tradition of such earlier Universal serials as Flash Gordon and Jungle Jim, the 12-chapter Radio Patrol was based on a popular comic strip, this one created by Eddie Sullivan and Charlie Schmidt. Grant Withers heads the cast as "radio cop" Pat O'Hara, at present the protector of young Pinky Adams (Mickey Rentschler). Pinky's father, the inventor of a new bulletproof steel, has been murdered, and the villains intend to kidnap the boy and force him to reveal his dad's secret formula. With the help of Molly Selkirk (Katherine Hughes), Pat prevents the bad guys from getting their slimy hands on Pinky. He also proves that the mastermind behind the crooks is the highly respected owner of a huge steel factory. Featured prominently in the cast is the talented German shepherd Silver Wolf, here cast as "Irish."