Endocrine Disruption: Biological Basis for Health Effects in Wildlife and Humans

Endocrine Disruption: Biological Basis for Health Effects in Wildlife and Humans

ISBN-10:
0195137493
ISBN-13:
9780195137491
Pub. Date:
04/28/2005
Publisher:
Oxford University Press, USA
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Overview

Endocrine Disruption: Biological Basis for Health Effects in Wildlife and Humans

This book addresses the biological effects of the reasonably large number of classes of compounds that have been recognized as endocrine disrupters. These compounds have been found to persist as pollutants in the environment, and have been blamed for causing developmental disorders and/or fertility problems in fish, amphibians, reptiles, birds, and possibly humans. This book presents the relevant fundamentals of the endocrine systems of animals and humans, the toxicology, developmental toxicology, ecology, and risk assessment methods, and lays out the current state of understanding for the whole field, organized by the classes of compounds that have been identified as endocrine disrupters.

Product Details

ISBN-13: 9780195137491
Publisher: Oxford University Press, USA
Publication date: 04/28/2005
Edition description: New Edition
Pages: 496
Product dimensions: 9.20(w) x 6.40(h) x 1.10(d)

Table of Contents

Part I. Vertebrate Chemical Regulation
1. Introduction to Endocrinology, David O. Norris and James A. Carr
2. Hormone Action on Receptors, Miles Orchinik and Catherine Propper
3. The Hypothalamus-Pituitary Axis, James A. Carr and David O. Norris
4. The Thyroid Gland, James A. Carr and David O. Norris
5. The Adrenal Glands, James A. Carr and David O. Norris
6. The Gonads, James A. Carr and David O. Norris
Part II. Toxicology and Risk Assessment
7. Introduction to the Science of Toxicology, Richard L. Dickerson and Ernest E. Smith
8. Probablistic Risk Assessment, Kenneth R. Dixon and Clyde F. Martin
9. Fish and Wildlife as Sentinels of Environmental Contamination, Lynn Frame and Richard L. Dickerson
Part III. Representative EDCs in Animals
10. Polychlorinated Dibenzo-p-Dioxins: Potential Mechanisms and Risk as Endocrine Disruptors, Mary K. Walker
11. Toxicology of PDBs and Related Compounds, John P. Giesy, K. Kannan, Alan L. Blankenship, Paul D. Jones, and J.L. Newsted
12. DDT and Its Analogues: New Insights into Their Endocrine-Disrupting Effects on Wildlife, Louis J. Guillette, Jr., Stefan A.E. Kools, Mark P. Gunderson, and Dieldrich S. Bermudez
13. Heavy Metals, Alice Hontela and Alexandra Lacroix
14. Effects of Alkyphenolic Compounds on Wildlife, Werner Kloas
15. Endocrine-Active Phytochemicals: Environmental Signaling Context and Mechanisms, Alan M. Vajda and David O. Norris
16. Triazines, Timothy S. Gross and R. Heath Rauschenberger
Appendices

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