There is great concern regarding the reproductive and health hazards of endocrine disruptors. Research indicates that men are experiencing declining fertility and an increased incidence of prostate cancer, while women are dealing with increased infertility, early menopause, and breast cancer. As new research reveals the previously unknown risks of
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Table of ContentsEffect on the Female Reproductive System. Disruption of Nongenomic Steroid Actions on Gametes and Serotonergic Pathways Controlling Reproductive Neuroendocrine Function by Environmental Chemicals. Developmental and Reproductive Abnormalities Associated with Environmental Estrogens: Diethylstilbestrol (DES) as an Example. Ovotoxic Environmental Chemicals: Indirect Endocrine Disruptors. p,p'-DDE and HCB: Mechanisms of Toxicity to Fetal and Embryonic Mammalian Cells. Dietary Phytoestrogens. Estrogens, Xenoestrogens and the Development of Neoplasms. Molecular Mechanisms of Endocrine Disruption in Estrogen Dependent Processes. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Environmental Antiestrogens: Characterization and Mechanism of Action. Effect on the Male Reproductive System. Endocrine Disruptors and Male Infertility. Environmental Androgens and Antiandrogens: An Expanding Chemical Universe. Endocrine Disruptors and Male Sexual Dysfunction. Prostate Development: Mechanisms for Opposite Effects of Low and High Doses of Estrogenic Chemicals. Metal Ions as Endocrine Disruptors: Implications for Prostate Cancer.