Endocrine Management of Breast Cancer

Endocrine Management of Breast Cancer

Hardcover

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Product Details

ISBN-13: 9781901865721
Publisher: Taylor & Francis
Publication date: 05/30/2002
Pages: 296
Product dimensions: 7.50(w) x 10.00(h) x 0.90(d)

Table of Contents

Part 1: The Use of Endocrine Therapies in Clinical Practice. Overview/Concepts. Ovarian Ablation. Pharmacology, Biology, and Clinical Use of Triphenylethylenes. Selective Estrogen Receptor Modulators (SERMs). Fulvestrant (ICI 182,780, Faslodex): A "Pure" Antiestrogen. Aromatase Inhibitors in Breast Cancer. Progestational agents. The Clinical Efficacy of Progesterone Antagonists in Breast Cancer. Part 2: Biological Aspects of Endocrine Therapies. Cellular and Molecular Actions of Estrogens and Antiestrogens in Breast Cancer. Clinical Response and Resistance to SERMs. Animal Models of Endocrine-responsive and -unresponsive Breast Cancers. Biological Changes in Primary Breast Cancer during Antiestrogen Therapies. Effects of Aromatase Inhibitors on Breast Cancer. Effects of Progesterone Receptor Antagonists on Breast Cancer. Part 3: Future Strategies. Future Prospects for the Endocrine Management of Breast Cancer.

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