The initial discoveries over a decade ago of the opiate receptor and several natural, opioid ligands heralded an explosion of research into the anatomy, pharmacology and biochemistry of the endogenous opioid systems. This contributed volume brings together a series of authoritative chapters that critically examine major areas of contemporary behavioral research on opiates and the endogenous opioid systems. Discusses the three opioid peptide families, ligand-receptor selectivity, classic effects of opiates and related substances, and endogenous opioids in the regulation of food intake and the controls of drinking and water balance. Behavioral processes with which opioid mechanisms have been associated are also examined including social attachment and social interaction, sexual behavior, exploration and activity, and learning and memory.
|Product dimensions:||6.30(w) x 9.25(h) x 0.98(d)|
Table of Contents
Overview of the Endogenous Opioid Systems: Anatomical, Biochemical and Functional Issues (H. Akil, et al.).
Physiological Dependence on Opioids (D. Gmerek).
Opioid Reinforcement Processes (M. Bozarth).
Tolerance, Endorphins and Other Aspects of Opiate Drug Discrimination (F. Colpaert & G. Shearman).
Environmentally Induced Analgesia: Situational Factors, Mechanisms and Significance (R. Rodgers & J. Randall).
Endorphins, Opiates and Food Intake (S. Cooper, et al.).
Evidence for Opioid Involvement in Controls of Drinking and Water Balance (S. Cooper).
The Role of Opioid Mechanisms in Social Interaction and Attachment (D. Benton & P. Brain).
Endorphins and Sexual Behaviour (G. Serra, et al.).
Endorphins, Exploration and Activity (R. Katz).
Opioid Modulation of Learning and Memory: Multiple Behavioral Outcomes (R. Messing).
Endogenous Opioid Systems and Neurobehavioral Development (I. Zagon & P. McLaughlin).
Neurochemical Methods in the Study of the Role of Endorphins in Psychiatric Disorders (F. Nyberg & L. Terenius).
Narcotic Antagonist and Opioid Treatment in Psychiatry (C. Schmauss & H. Emrich).