Epigenetics and Disease: Pharmaceutical Opportunities

Epigenetics and Disease: Pharmaceutical Opportunities


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Product Details

ISBN-13: 9783034803052
Publisher: Springer Basel
Publication date: 02/25/2012
Series: Progress in Drug Research , #67
Edition description: 2011
Pages: 270
Product dimensions: 6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

1 DNA Methylation and Cancer
Phillippa C. Taberlay and Peter A. Jones

2 Genome-wide Epigenetic Modifications in Cancer
Yoon Jung Park, Rainer Claus, Dieter Weichenhan and Christoph Plass

3 DNA Repair and the Control of DNA Methylation
Primo Schär and Olivier Fritsch

4 Errors in Erasure: Links Between Histone lysine Methylation Removal and Disease
Elizabeth M. Duncan and C. David Allis

5 Histone Modifications in Cancer Biology and Prognosis
Siavash K. Kurdistani

6 Dynamics of Histone Lysine Methylation: Structures of Methyl Writers and Eraser
Anup K. Upadhyay and Xiaodong Cheng

7 Epigenetic Mechanisms of Mental Retardation
Anne Schaefer, Alexander Tarakhovsky and Paul Greengard

8 Histone and DNA Modifications in Mental Retardation
Shigeki Iwase and Yang Shi

9 HDAC Inhibitors and Cancer Therapy
Peter W. Atadja

10 Epigenetic Mechanisms in Acute Myeloid Leukemia
Antoine H.F.M. Peters and Juerg Schwaller

11 The Liver-Specific MicroRNA miR-122: Biology and Therapeutic Potential
Witold Filipowicz and Helge Großhans

12 Transcriptional Regulatory Networks in Embryonic Stem Cells
Yun Shen Chan, Lin Yang, Huck-Hui Ng

13 Small Molecules in Cellular Reprogramming and Differentiation
Xu Yuan, Wenlin Li and Sheng Ding

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