ISBN-10:
1118027795
ISBN-13:
9781118027790
Pub. Date:
08/30/2011
Publisher:
Wiley
Epistemology of the Cell: A Systems Perspective on Biological Knowledge / Edition 1

Epistemology of the Cell: A Systems Perspective on Biological Knowledge / Edition 1

by Edward R. Dougherty, Michael L. Bittner

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Product Details

ISBN-13: 9781118027790
Publisher: Wiley
Publication date: 08/30/2011
Series: IEEE Press Series on Biomedical Engineering Series , #34
Pages: 216
Product dimensions: 6.30(w) x 9.30(h) x 0.70(d)

About the Author

EDWARD R. DOUGHERTY, PhD, is Director of the Genomic SignalProcessing Laboratory at Texas A&M University, where he holdsthe Robert M. Kennedy '26 Chair and is Professor in the Departmentof Electrical and Computer Engineering. He is also co-Director ofthe Computational Biology Division at the Translational GenomicsResearch Institute as well as Adjunct Professor in the Departmentof Bioinformatics and Computational Biology, M. D. Anderson CancerCenter at the University of Texas. Dr. Dougherty has published morethan 300 peer-reviewed journal articles and book chapters.

MICHAEL L. BITTNER, PhD, is co-Director and SeniorInvestigator at the Computational Biology Division at theTranslational Genomics Research Institute. Previously, he wasassociate investigator in the Cancer Genetics Branch of theNational Human Genome Research Institute at the National Institutesof Health. Dr. Bittner holds a dozen patents and has published morethan 100 articles.

Table of Contents

Preface ix

Acknowledgments xi

1. Science and Knowledge 1

2. Causality and the Three Pillars of Aristotelian Science11

3. Scientific Knowledge 35

4. Cells and Factories 59

5. Translational Science 85

6. Stochastic Validation: Classifi ers 97

7. Stochastic Validation: Networks 129

8. Sola Fides 147

9. Model-based Experimentation in Biology 169

References 189

Index 197

IEEE Press Series on Biomedical Engineering 203

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