Evolution after Gene Duplication / Edition 1

Evolution after Gene Duplication / Edition 1

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Evolution after Gene Duplication / Edition 1

Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity.

Key Features:

  • Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system)
  • A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways
  • Taps the significant increase in multi-gene family data that has resulted from comparative genomics
  • Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication

This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.

Product Details

ISBN-13: 9780470593820
Publisher: Wiley
Publication date: 10/05/2010
Pages: 358
Product dimensions: 7.20(w) x 10.00(h) x 0.90(d)

Table of Contents

Contributors vii

Preface xi

1 Understanding Gene Duplication Through Biochemistry and Population Genetics David A. Liberles Grigory Kolesov Katharina Dittmar 1

2 Functional Divergence of Duplicated Genes Takashi Makino David G. Knowles Aoife McLysaght 23

3 Duplicate Retention After Small- and Large-Scale Duplications Steven Maere Yves Van de Peer 31

4 Gene Dosage and Duplication Fyodor A. Kondrashov 57

5 Myths and Realities of Gene Duplication Austin L. Hughes Robert Friedman 77

6 Evolution After and Before Gene Duplication" Tobias Sikosek Erich Bornberg-Bauer 105

7 Protein Products of Tandem Gene Duplication: A Structural View William R. Taylor Michael I. Sadowski 133

8 Statistical Methods for Detecting Functional Divergence of Gene Families Xun Gu 163

9 Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework Athanasia C. Tzika Raphael Helaers Michel C. Milinkovitch 173

10 Reconciling Phylogenetic Trees Oliver Eulenstein Snehalata Huzurbazar David A. Liberles 185

11 On the Energy and Material Cost of Gene Duplication Andreas Wagner 207

12 Fate of a Duplicate in a Network Context Orkun S. Soyer 215

13 Evolutionary and Functional Aspects of Genetic Redundancy Ran Kafri Tzachi Pilpel 229

14 Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds Chris L. Organ Matthew D. Rasmussen Maude W. Baldwin Manolis Kellis Scott V. Edwards 253

15 Gene and Genome Duplications in Plants Pamela S. Soltis J. Gordon Burleigh Andre S. Chanderbali Mi-Jeong Yoo Douglas E. Soltis 269

16 Whole Genome Duplications and the Radiation of Vertebrates Shigehiro Kuraku Axel Meyer 299

Index 313

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