Frontotemporal Dementia Syndromes

Frontotemporal Dementia Syndromes

by John R. Hodges
Pub. Date:
Cambridge University Press
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Frontotemporal Dementia Syndromes

In the past decade there have been enormous advances in our understanding of frontotemporal dementia and related syndromes. The impetus for these advances has come from a number of directions, including genetic discoveries, new approaches to neuroimaging and improved neuropsychological understanding of the cognitive aspects of the condition. This book provides a much needed review of the current status of our knowledge of these syndromes.

The book starts with chapters reviewing the history of the condition and describes the presenting clinical, neuropsychiatric and neuropsychological features, before reviewing, in detail, the areas of greatest recent research progress: brain imaging, histopathology and molecular genetics. The book concludes with a chapter proposing a multidisciplinary approach to patient management, with illustrative case studies.

Frontotemporal Dementia Syndromes will be essential reading for neurologists, psychologists, psychiatrists and other clinicians interested in cognitive and behavioural disorders, as well as for basic scientists working in the area of neurodegeneration.

Product Details

ISBN-13: 9780521184151
Publisher: Cambridge University Press
Publication date: 02/17/2011
Pages: 358
Product dimensions: 6.70(w) x 9.60(h) x 0.60(d)

Table of Contents

List of contributors     vii
Preface     ix
Overview of frontotemporal dementia   John R. Hodges     1
Epidemiology of frontotemporal dementia   Andrew Graham     25
Clinical presentations of frontotemporal dementia   Christopher M. Kipps   Jonathan A. Knibb   John R. Hodges     38
Overlap syndromes   Thomas H. Bak     80
The neuropsychology of frontotemporal dementia   John R. Hodges   Karalyn Patterson     102
Neuroimaging and other investigative findings   Peter J. Nestor     134
The histopathology of frontotemporal dementia   R. Rhys Davies   John H. Xuereb     161
Molecular neuropathology in familial and sporadic frontotemporal dementia   Laura Gasparini   Maria Grazia Spillantini     208
The genetics of frontotemporal dementia   Jeremy Brown     257
Psychological interventions in frontotemporal dementia   Sinclair Lough   Vanessa Garfoot     277
Index     326

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