In the past decade there have been enormous advances in our understanding of frontotemporal dementia and related syndromes. The impetus for these advances has come from a number of directions, including genetic discoveries, new approaches to neuroimaging and improved neuropsychological understanding of the cognitive aspects of the condition. This book provides a much needed review of the current status of our knowledge of these syndromes.
The book starts with chapters reviewing the history of the condition and describes the presenting clinical, neuropsychiatric and neuropsychological features, before reviewing, in detail, the areas of greatest recent research progress: brain imaging, histopathology and molecular genetics. The book concludes with a chapter proposing a multidisciplinary approach to patient management, with illustrative case studies.
Frontotemporal Dementia Syndromes will be essential reading for neurologists, psychologists, psychiatrists and other clinicians interested in cognitive and behavioural disorders, as well as for basic scientists working in the area of neurodegeneration.
|Publisher:||Cambridge University Press|
|Product dimensions:||6.70(w) x 9.60(h) x 0.60(d)|
Table of Contents
List of contributors vii
Overview of frontotemporal dementia John R. Hodges 1
Epidemiology of frontotemporal dementia Andrew Graham 25
Clinical presentations of frontotemporal dementia Christopher M. Kipps Jonathan A. Knibb John R. Hodges 38
Overlap syndromes Thomas H. Bak 80
The neuropsychology of frontotemporal dementia John R. Hodges Karalyn Patterson 102
Neuroimaging and other investigative findings Peter J. Nestor 134
The histopathology of frontotemporal dementia R. Rhys Davies John H. Xuereb 161
Molecular neuropathology in familial and sporadic frontotemporal dementia Laura Gasparini Maria Grazia Spillantini 208
The genetics of frontotemporal dementia Jeremy Brown 257
Psychological interventions in frontotemporal dementia Sinclair Lough Vanessa Garfoot 277