This text uses a more brief and qualitative approach to present biochemistry with chemical rigor, focusing on the structures of biomolecules, chemical mechanisms, and evolutionary relationships. It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries.
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Table of ContentsINTRODUCTION.
Nucleotides and Nucleic Acids.
Proteins: Primary Structure.
Proteins: Three-Dimensional Structure.
Enzyme Kinetics, Inhibition, and Regulation.
Introduction to Metabolism.
Glycogen Metabolism and Gluconeogenesis.
Citric Acid Cycle.
Electron Transport and Oxidative Phosphorylation.
Amino Acid Metabolism.
Mammalian Fuel Metabolism: Integration and Regulation.
GENE EXPRESSION AND REPLICATION.
Nucleic Acid Structure.
DNA Replication, Repair, and Recombination.
Transcription and RNA Processing.
Regulation of Gene Expression.
Solutions to Problems.