Gene Therapy for Autoimmune and Inflammatory Diseases

Gene Therapy for Autoimmune and Inflammatory Diseases


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Product Details

ISBN-13: 9783034601641
Publisher: Springer Basel
Publication date: 07/16/2010
Series: Milestones in Drug Therapy
Edition description: 2010
Pages: 239
Product dimensions: 6.60(w) x 9.20(h) x 0.80(d)

Table of Contents

List of Contributors vii

Preface xi

Gene therapy for arthritis Florence Apparailly Paul Peter Tak Christian Jorgensen 1

Gene therapy for the treatment of inflammatory bowel disease Melanie A. Ruffner Scott E. Plevy Anthony T. Cheung 19

Gene therapy for diabetes Hirofumi Noguchi 39

Gene therapy for cystic fibrosis lung disease Stephanie G. Sumner-Jones Deborah R. Gill Stephen C. Hyde 47

Gene therapy of multiple sclerosis Roberto Furlan Chiara Maiorino Alberto Gatta Francesca Ruffini Gianvito Martino 65

Gene therapy for myositis Hans H. Jung Juliane Bremer Michael Weller 79

Gene therapy for osteoarthritis Steven C. Ghivizzani Christopher H. Evans 91

Gene therapy: Sjögren's syndrome Nienke Roescher Paul Peter Tak John A. Chiorini 113

Disease mechanisms, genetic susceptibility and therapeutic approaches in lupus disease Rizgar A. Mageed Taher E. Taher Ali S. Jawad 127

Regulated promoters Jeoroen Geurts Wim B. van den Berg Fons A.J. van de Loo 147

Development of AAV vectors for the therapy of autoimmune and inflammatory diseases Chengwen Li Matthew L. Hirsch R. Jude Samulski 161

Delivery and application of plasmid DNA in arthritis gene therapy Maria C. Subang David J. Gould 181

Helper-dependent adenoviral vectors Nicola Brunetti-Pierri Philip Ng 193

Cells as carriers of gene therapy Ingo H. Tarner 209

Perspectives for the future developments of gene therapy for autoimmune and inflammatory therapy Yuti Chernajovsky Paul D. Robbins 223

Index 233

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