Pub. Date:
Cold Spring Harbor Laboratory Press
Genetics of Complex Human Diseases: A Laboratory Manual

Genetics of Complex Human Diseases: A Laboratory Manual

by Ammar Al-Chalabi, Laura Almasy
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Product Details

ISBN-13: 9780879698836
Publisher: Cold Spring Harbor Laboratory Press
Publication date: 11/28/2009
Edition description: Lab Manual
Pages: 250
Product dimensions: 8.40(w) x 10.80(h) x 0.50(d)

Table of Contents

1. Introduction
Ammar Al-Chalabi and Laura Almasy
2. "Statistics 101"—A Primer for the Genetics of Complex Human Diseases
Janet Sinsheimer
3. Linkage Analysis of Discrete Traits
Ingrid B. Borecki and John P. Rice
4. Epidemiologic Considerations in Complex Disease Genetics
John Gallacher
5. Variance Component Methods for Analysis of Complex Phenotypes
Laura Almasy and John Blangero
6. Multiple Testing and Power Calculations in Genetic Association Studies
Hon-Cheong So and Pak C. Sham
7. Introduction to Genetic Association Studies
Cathryn M. Lewis and Jo Knight
8. Genome-Wide Association Studies
Ammar Al-Chalabi
9. Introduction to Linkage Disequilibrium, the HapMap, and Imputation
Benjamin M. Neale
10. Meta-Analysis of Genome-Wide Association Studies
Paul I.W. de Bakker, Benjamin M. Neale, and Mark J. Daly
11. Gene-Environment Interaction and Common Disease
Ruth J.F. Loos and Nicholas J. Wareham
12. Family-Based Genetic Association Tests
Eden R. Martin and Evadnie Rampersaud
13. Copy-Number Variation and Common Human Diseases
Dheeraj Malhatra and Jonathan Sebat
14. Oncogenomics
Simon J. Furney, Gunes Gundem, and Nuria Lopez-Bigas
15. When the Genetic Code Is Not Enough—How Sequence Variations Can Affect Pre-mRNA Splicing and Cause (Complex) Disease
Brage Storstein Andresen and Adrian R. Krainer
16. Laboratory Methods for High-Throughput Genotyping
Howard J. Edenberg and Yunlong Liu
17. Gene Set Analysis and Network Analysis for Genome-Wide Association Studies
Inti Pedroso and Gerome Breen

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Genetic Variation: A Laboratory Manual
Proteomics: A Cold Spring Harbor Laboratory Course Manual
Statistics at the Bench: A Step-by-Step Handbook for Biologists

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