Genetics of Fitness and Physical Performance / Edition 1

Genetics of Fitness and Physical Performance / Edition 1

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Human Kinetics Publishers

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Genetics of Fitness and Physical Performance / Edition 1

Genetics of Fitness and Physical Performance is the first comprehensive reference on the role of the genes in influencing individual variation in fitness and performance.

This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes. Focusing on the interests of sport scientists, the authors provide insight into the significance of this research on nearly every aspect of the study of human physical activity.

The book presents the biological basis of heredity and explains the concepts and methods of genetic epidemiology and molecular biology that are necessary to understand this specialized field. With the rapid advances in molecular biology and the paradigms of human genetics, exercise scientists face a dynamic and vibrant new field. This book offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension by searching for single gene effects and identifying susceptibility genes.

The authors review the evidence on the role of the genes for human traits as it pertains to the exercise science field. And they explore the scientific, practical, and ethical issues that confront exercise scientists as progress is made in this field.

Genetics of Fitness and Physical Performance is vital reading for scholars in the field of exercise and sport science to understand how recent discoveries in genetics might shape their future research.

Product Details

ISBN-13: 9780873229517
Publisher: Human Kinetics Publishers
Publication date: 05/21/1997
Edition description: New Edition
Pages: 408
Product dimensions: 6.00(w) x 9.00(h) x 1.17(d)
Age Range: 18 Years

Table of Contents

Chapter 1. Introduction

-Statement of the Problem

-Nature Versus Nurture

-The Growing Power of the Biological Sciences

-Necessary and Susceptibility Genes and Other Effects

-The International Effort to Study the Human Genome

-Content of the Book

Chapter 2. The Human Genome

-The Human Genome

-The Structure of DNA

-From DNA to RNA to Proteins

-The Human Gene

-Genes and Proteins

-Regulation of Gene Expression

-Mitochondrial DNA


Chapter 3. Detection and Extent of Human Genetic Variation

-Chromosomal Anomalies

-Mutation and Genetic Variation

-Genetic Polymorphism

-Recombinant-DNA Technology

-Detection of Genetic Variation

-Extent of DNA Variation


Chapter 4. Understanding the Methods

-Overview of Research Strategies

-Human Studies

-Assessment of Familial Aggregation

-Assessment of Heritability

-Detection of Major or Single Gene Effects

-Detection of Genotype-Environment Interaction

-Animal Studies


Chapter 5. Defining Performance, Fitness, and Health

-Performance-Related Fitness

-Health-Related Fitness


-Individual Differences in Trainability

-Determinants of Trainability


Chapter 6. Genetics and Health Status

-Measuring Health Status

-Genetic Effects in Health Status

-Longevity and Aging


Chapter 7. Genetics of Metabolic Rate and Activity Level

-Life Span and Gender Variability

-Genetics of Resting Metabolic Rate and Thermic Effect of Food

-Genetics of Activity Level


Chapter 8. Genetics of Dietary Intake

-Life Span and Gender Variability

-Genetics of Dietary Intake

-Taste Preferences

-Eating Behavior

-Gene-Nutrient Interactions


Chapter 9. Genetics of Body Size and Physique Phenotypes

-Life Span and Gender Variability

-Genetics of Morphological Phenotypes


Chapter 10. Genetics of Body Fat and Fat Distribution

-The Phenotypes

-Life Span, Gender, and Population Variability

-Genetic Epidemiology

-Genetic-Environment Interactions

-Contribution of Specific Genes

-Genetics and Regional Fat Distribution

-Is Obesity Inherited?


Chapter 11. Genetics and Skeletal Muscle Phenotypes

-Gender and Age Difference in Muscle

-Genetics of Skeletal Muscle Tissue Phenotypes

-Genotype Training Interaction Effects in Skeletal Muscle


Chapter 12. Genetics of Cardiorespiratory Fitness Phenotypes

-Life Span and Gender Variability

-Genetics of Cardiac Structures and Functions

-Genetics of Pulmonary Function

-Genetics of Blood Pressure


Chapter 13. Genetics of Metabolic Fitness Phenotypes and Other Risk Factors

-Life Span and Gender Variability

-Blood Lipids, Lipoproteins, and Apolipoproteins

-Glucose and Insulin

-Substrate Oxidation

-Blood Coagulation and Fibrinolytic Systems


-Other Risk Factors

-Genotype-Environment Interaction

-The Metabolic Syndrome


Chapter 14. Genetics and Motor Development

-Changes During the Life Span

-Genetics and Early Motor Development

-Genetics and Movement Patterns

-Motor Development in Individuals with Genetic Anomalies


Chapter 15. Genetics and Performance

-Life Span and Gender Variability

-Overview of Genetic Studies

-Muscular Strength and Endurance

-Motor Performance

-Modeling Twin and Familial Resemblance

-Responses to Training

-Molecular Markers


Chapter 16. Molecular Medicine and Health-Related Fitness

-Single Gene Diseases

-Common Multifactoral Diseases

-The Era of Molecular Medicine

-Definition of Susceptibility and Risk at the Molecular Level

-Implications for Health-Related Fitness

-A Vision of the Year 2500


Chapter 17. Genes and High Performance Sports

-Science and High-Performance Sports

-Current Understanding of the Role of Genes

-Talent Detection

-Dramatic Changes to be Expected


Chapter 18. Ethical Issues

-Implications for Society

-Considerations for the Exercise Scientist

-Considerations for Sport Governing Bodies



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