Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods / Edition 1

Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods / Edition 1

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Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods / Edition 1

The nutraceutical and functional food field is rapidly growing in diverse sectors, including academic, commercial, and government. This has brought a corresponding shift in research focus and in public awareness. Understanding the relevance of the scientific principles in determining the safety and effectiveness of functional foods and nutraceuticals is increasingly important. It is becoming increasingly evident that genomic research technologies will be used in the coming years and there is a need to provide resources that will facilitate this growth. Genomics, Proteomics &w Metabolomics in Nutraceuticals & Functional Foods incorporates the most recent advances in the three major sectors of the field within one volume. Genomics, proteomics, and metobolomics represent three major scientific research areas that contribute to nutraceutical and functional food research for studies of effectiveness and safety.

Special features include:

Recent advances in the areas of genomics, proteomics, and metabolomics in nutraceutical research

Dedicated chapters on the application of "-omics" in personalized nutrition and personalized phytomedicine

Chapter contributions by an international panel of experts

Product Details

ISBN-13: 9780813814025
Publisher: Wiley
Publication date: 04/05/2010
Pages: 352
Product dimensions: 6.90(w) x 9.70(h) x 0.90(d)

About the Author

Debasis Bagchi, Ph.D., Adjunct Professor of Medicinal Chemistry, Pharmacological and Pharmaceutical Sciences Department, University of Houston, TX.

Francis Lau, InterHealth USA, Benecia, CA.

Manashi Bagchi, Ph.D., InterHealth USA, Benecia, CA.

Table of Contents

Editors and Contributors ix

Preface xiii

Section 1 Introduction

1 Recent advances in nutraceuticals and functional foods Francis C. Lau Debasis Bagchi Shirley Zafra-Stone Manashi Bagchi 3

2 Novel omics technologies in nutraceutical and functional food research Xuewu Zhang Wei Wang Kaijun Xiao 11

Section 2 Genomics

3 Nutrigenomics and statistical power: The ethics of genetically informed nutritional advice Ruth Chadwick 23

4 NutrimiRomics: The promise of a new discipline in nutrigenomics Chandan K. Sen 35

5 Genomics in weight loss nutraceuticals Debasis Bagchi Francis C. Lau Hiroyoshi Moriyama Manashi Bagchi Shirley Zafra-Stone 45

6 Application of genomics and bioinformatics analysis in exploratory study of functional food Kohsuke Hayamizu Aiko Manji 61

7 Genomics as a tool to characterize anti-inflammatory nutraceuticals Sashwati Roy 73

8 Application of nutrigenomics in gastrointestinal health Lynnette R. Ferguson Philip I. Baker Donald R. Love 83

9 Genomics analysis to demonstrate the safety and efficacy of dietary antioxidants Nilanjana Maulik 95

10 Genomics applied to nutrients and functional foods in Japan: State of the art Yuji Nakai Akihito Yasuoka Hisanori Kato Keiko Abe 127

11 Genomic basis of anti-inflammatory properties of Boswellia extract Golakoti Trimurtulu Chandan K. Sen Alluri V. Krishnaraju Krishanu Sengupta 155

12 Nutrigenomic Perspectives on Cancer Chemoprevention with Anti-inflammatory and Antioxidant Phytochemicals: NF-kB and Nrf2 Signaling Pathways as Potential Targets Hye-Kyung Na Young-Joon Surh 175

Section 3 Proteomics

13 Proteomics analysis of the functionality of Toona sinensis by 2D-gel electrophoresis Sue-Joan Chang Chun-Yung Huang 201

14 Application of proteomics in nutrition research Baukje de Roos 213

15 Proteomics approach to assess the potency of dietary grape seed proanthocyanidins Hai-qing Gao 225

16 Proteomics and its application for elucidating insulin deregulation in diabetes Hyun-Jung Kim Chan-Wha Kim 241

Section 4 Metabolomics

17 NMR-based-metabolomics strategy for the classification and quality control of nutraceuticals and functional foods Yulan Wang Huiru Tang 265

18 Metabolomics: An emerging post-genomic tool for nutrition Phillip Whitfield Jennifer Kirwan 271

19 Evaluation of the beneficial effects of phytonutrients by metabolomics Katia Nones Silas G. Villas-Bôas 287

Section 5 Nutrigenomics in Human Health

20 Omics for the development of novel phytomedicines Kandan Aravindaram Harry Wilson Ning-Sun Yang 299

21 Contribution of omics revolution to cancer prevention research Nancy J. Emenaker John A. Milner 315

Index 329

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