Goodman and Gilman Manual of Pharmacology and Therapeutics, Second Edition / Edition 2

Goodman and Gilman Manual of Pharmacology and Therapeutics, Second Edition / Edition 2

Pub. Date:
McGraw-Hill Professional Publishing
Select a Purchase Option (List)
  • purchase options
    $22.24 $73.00 Save 70%
    • Free return shipping at the end of the rental period details
    • Textbook Rentals in 3 Easy Steps  details
    Note: Access code and/or supplemental material are not guaranteed to be included with textbook rental or used textbook.
  • purchase options
    $57.12 $73.00 Save 22% Current price is $57.12, Original price is $73. You Save 22%.
  • purchase options


Goodman and Gilman Manual of Pharmacology and Therapeutics, Second Edition / Edition 2

A full-color manual derived from Goodman & Gilman's The Pharmacological Basis of Therapeutics

A Doody's Core Title for 2017!

Goodman & Gilman's The Manual of Pharmacology and Therapeutics offers concise, authoritative coverage of class-specific and disease-specific drugs, organized primarily by organ/system. Derived from Goodman & Gilman's Pharmacological Basis of Therapeutics, Twelfth Edition and further updated, this streamlined text focuses on the principles of medical pharmacology and drug therapy and delivers coverage of all major drug classes.

More than a pocket drug guide, this powerful resource covers:

  • General Principles
  • Neuropharmacology
  • Modulation of Cardiovascular, Pulmonary, and Renal Function
  • Inflammation, Immunomodulation, and Hematopoiesis
  • Hormones and Hormone Antagonists
  • Drugs Affecting Gastrointestinal Function
  • Chemotherapy of Microbial Diseases
  • Chemotherapy of Neoplastic Diseases
  • Special Systems Pharmacology, including Environmental Toxicology

The text explains the physiology and pathophysiology of major organ systems and pathogens with respect to pharmacotherapy and the mechanisms of drug action. With a new full color design and numerous tables, charts, and illustrations that highlight, explain, and summarize important information, Goodman & Gilman's Manual of Pharmacology and Therapeutics is essential wherever knowledge of drug actions and interactions is required. Nursing, pharmacy, and medical students will find the Manual to be a concise and authoritative textbook.

Product Details

ISBN-13: 9780071769174
Publisher: McGraw-Hill Professional Publishing
Publication date: 12/30/2013
Edition description: List
Pages: 1216
Sales rank: 680,647
Product dimensions: 6.00(w) x 9.00(h) x 1.60(d)

Table of Contents

Preface ix

Section I General Principles 1

1 Drug Invention and the Pharmaceutical Industry 1

2 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination 12

3 Pharmacodynamics: Molecular Mechanisms of Drug Action 27

4 Drug Toxicity and Poisoning 50

5 Membrane Transporters and Drug Response 63

6 Drug Metabolism 81

7 Pharmacogenetics 98

Section II Neuropharmacology 111

8 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems 111

9 Muscarinic Receptor Agonists and Antagonists 138

10 Anticholinesterase Agents 148

11 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia 158

12 Adrenergic Agonists and Antagonists 171

13 5-Hydroxytryptamine (Serotonin) and Dopamine 200

14 Neurotransmission and the Central Nervous System 219

15 Drug Therapy of Depression and Anxiety Disorders 238

16 Pharmacotherapy of Psychosis and Mania 251

17 Hypnotics and Sedatives 267

18 Opioids, Analgesia, and Pain Management 281

19 General Anesthetics and Therapeutic Gases 310

20 Local Anesthetics 334

21 Pharmacotherapy of the Epilepsies 344

22 Treatment of Central Nervous System Degenerative Disorders 362

23 Ethanol and Methanol 376

24 Drug Addiction 387

Section III Modulation of Cardiovascular Function 401

25 Regulation of Renal Function and Vascular Volume 401

26 Renin and Angiotensin 435

27 Treatment of Myocardial Ischemia and Hypertension 450

28 Pharmacotherapy of Congestive Heart Failure 477

29 Anti-Arrhythmic Drugs 494

30 Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs 523

31 Drug Therapy for Hypercholesterolemia and Dyslipidemia 544

Section IV Inflammation, Immunomodulation, and Hematopoiesis 561

32 Histamine, Bradykinin, and Their Antagonists 561

33 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor 575

34 Pharmacotherapy of Inflammation, Fever, Pain, and Gout 587

35 Immunosuppressants, Tolerogens, and Immunostimulants 614

36 Pulmonary Pharmacology 631

37 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins 650

Section V Hormones and Hormone Antagonists 669

38 Introduction to Endocrinology: The Hypothalamic-Pituitary Axis 669

39 Thyroid and Anti-Thyroid Drugs 684

40 Estrogens and Progestins 699

41 Androgens 717

42 Pharmacology of the Adrenal Cortex 726

43 Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia 743

44 Agents Affecting Mineral Ion Homeostasis and Bone Turnover 771

Section VI Drugs Affecting Gastrointestinal Function 789

45 Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease 789

46 Gastrointestinal Motility and Water Flux; Emesis; Biliary and Pancreatic Disease 799

47 Pharmacotherapy of Inflammatory Bowel Disease 819

Section VII Chemotherapy of Microbial Diseases 829

48 General Principles of Antimicrobial Therapy 829

49 Chemotherapy of Malaria 840

50 Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections 859

51 Chemotherapy of Helminth Infections 872

52 Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections 883

53 Penicillins, Cephalosporins, and Other β-Lactam Antibiotics 894

54 Aminoglycosides 913

55 Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents 923

56 Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy 942

57 Antifungal Agents 958

58 Antiviral Agents (Nonretroviral) 974

59 Antiretroviral Agents and Treatment of HIV Infection 993

Section VIII Chemotherapy of Neoplastic Diseases 1015

60 General Principles of Cancer Chemotherapy 1015

61 Cytotoxic Agents 1023

62 Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines 1063

63 Natural Products in Cancer Chemotherapy: Hormones and Related Agents 1080

Section IX Special Systems Pharmacology 1091

64 Ocular Pharmacology 1091

65 Dermatological Pharmacology 1114

66 Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders 1136

67 Environmental Toxicology: Carcinogens and Heavy Metals 1149

Appendix I Principles of Prescription Order Writing and Patient Compliance 1169

Index 1177

Customer Reviews

Most Helpful Customer Reviews

See All Customer Reviews