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McGraw-Hill Professional Publishing
Goodman and Gilman's The Pharmacological Basis of Therapeutics / Edition 12

Goodman and Gilman's The Pharmacological Basis of Therapeutics / Edition 12

by Laurence Brunton
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  • Product Details

    ISBN-13: 2900071624427
    Publisher: McGraw-Hill Professional Publishing
    Publication date: 12/20/2010
    Edition description: New Edition
    Pages: 1808
    Product dimensions: 8.50(w) x 10.50(h) x 3.00(d)

    About the Author


    Laurence L. Brunton, PhD

    Professor of Pharmacology and Medicine

    University of California San Diego

    School of Medicine

    La Jolla, CA

    Associate Editors:

    Bruce A. Chabner, MD

    Clinical Director

    MDF Cancer Center

    Professor of Medicine

    Harvard Medical School

    Boston, MA

    Bjorn Christian Knollmann, MD, PhD

    Associate Professor of Medicine and Pharmacology

    Oates Institute for Experimental Therapeutics

    Vanderbilt University School of Medicine

    Division of Clinical Pharmacology

    Nashville, TN

    Table of Contents


    Consultants to the Editors


    Preface to the First Edition


    1. Drug Invention and the Pharmaceutical Industry, Suzanne M. Rivera and Alfred Goodman Gilman

    2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination, Iain L. O. Buxton and Leslie Z. Benet

    3. Pharmacodynamics: Molecular Mechanisms of Drug Action, Donald K. Blumenthal and James C. Garrison

    4. Drug Toxicity and Poisoning, Kevin C. Osterhoudt and Trevor M. Penning

    5. Membrane Transporters and Drug Response, Kathleen M. Giacomini and Yuichi Sugiyama

    6. Drug Metabolism, Frank J. Gonzalez, Michael Coughtrie, and Robert H. Tukey

    7. Pharmacogenetics, Mary V. Relling and Kathleen M. Giacomini


    8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems, Thomas C. Westfall and David P. Westfall

    9. Muscarinic Receptor Agonists, Joan Heller Brown and Nora Laiken

    10. Anticholinesterase Agents, Palmer Taylor

    11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia, Ryan E. Hibbs and Alexander C. Zambon

    12. Adrenergic Agonists and Antagonists, Thomas C. Westfall and David P. Westfall

    13. 5-Hydroxytryptamine (Serotonin) and Dopamine, Elaine Sanders-Bush and Lisa Hazelwood

    14. Neurotransmission and the Central Nervous System, Perry B. Molinoff

    15. Drug Therapy of Depression and Anxiety Disorders, James M. O'Donnell and Richard C. Shelton

    16. Pharmacotherapy of Psychosis and Mania, Jonathan M. Meyer

    17. Hypnotics and Sedatives, S. John Mihic and r. Adron Harris

    18. Opioids, Analgesia, and Pain Management, Tony L. Yaksh and Mark S. Wallace

    19. General Anesthetics and Therapeutic Gases, Piyush M. Patel, Hemal H. Patel, and David M. Roth

    20. Local Anesthetics, William A. Catteral nad Kenneteh Mackie

    21. Pharmacotherapy of the Epilepsies, James O. McNamara

    22. Treatment of Central Nervous System Degenerative Disorders, David G. Standaert and Erik D. Roberson

    23. Ethanol and Methanol, Marc A. Schuckit

    24. Drug Addition, Charles P. O'Brien


    25. Regulation of Renal Function and Vascular Volume, Robert F. Reilly and Edwin K. Jackson

    26. Renin and Angiotensin, Randa Hilal-Dandan

    27. Treatment of Myocardial Ischemia and Hypertension, Thomas Michel and Brian B. Hoffman

    28. Pharmacotherapy of Congestive Heart Failure, Bradley A. Maron and Thomas P. Rocco

    29. Anti-Arrhythmic Drugs, Kevin J. Sampson and Robert S. Kass

    30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs, Jeffrey I. Weitz

    31. Drug Therapy for Hypercholesterolemia and Dyslipiedmia, Thomas P. Bersot


    32. Histamine, Bradykinin, and Their Antagonists, Randal A. Skidgel, Allen P. Kaplan, and Ervin G. Erdös

    33. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor, Emer M. Smyth, Tilo Grosser, and Garret A. Fitzgerald

    34. Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacology of Gout, Tilo Grosser, Emer Smyth, and Garret A. FitzGerald

    35. Immunosupressants, Tolerogens, and Immunostimulants, Alan M. Krensky, William M. Bennett, and Flavio Vincenti

    36. Pulmonary Pharmacology, Peter J. Barnes

    37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins, Kenneth Kaushansky and Thomas J. Kipps


    38. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis, Keith L. Parker and Bernard P. Schimmer

    39. Thyroid and Anti-Thyroid Drugs, Gregory A. Brent and Ronald J. Koenig

    40. Estrogens and Progestins, Ellis R. Levin and Stephen R. Hammes

    41. Androgens, Peter J. Snyder

    42. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex, Bernard P. Schimmer and John W. Funder

    43. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia, Alvin C. Powers and David D'Alessio

    44. Agents Affecting Mineral Ion Homeostatis and Bone Turnover, Peter A. Friedman


    45. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease, John L. Wallace and Keith A. Sharkey

    46. Treatment of Disorders of Bowel Motility and Water Flux: Anti-Emetics; Agents Used in Biliary and Pancreative Disease, Keith A. Sharkey and John L. Wallace

    47. Pharmacotherapy of Inflammatory Bowel Disease, John L. Wallace and Keith A. Sharkey


    48. General Principles of Antimicrobial Therapy, Tawanda Gumbo

    49. Chemotherapy of Malaria, Joseph M. Vinetz, Jerome Clain, Viengngeun Bounkeua, Richard T. Eastman, and David Fidock

    50. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections, Margaret A. Phillips, Samuel L. Stanley, Jr.

    51. Chemotherapy of Helminth Infections, James McCarthy, Alex Loukas, and Peter J. Hotez

    52. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections, William A. Petri, Jr.

    53. Penicillins, Cephalosporins, and Other ß-Lactam Antibiotics, William A. Petri, Jr.

    54. Aminoglycosides, Conan MacDougall and Henry F. Chambers

    55. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents, Conan MacDougall and Henry F. Chambers

    56. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy, Tawanda Gumbo

    57. Antifungal Agents, John E. Bennett

    58. Antiviral Agents (Nonretroviral), Edward P. Acosta and Charles Flexner

    59. Antiretroviral Agents and Treatment of HIV Infection, Charles Flexner


    60. General Principles of Cancer Chemotherapy, Bruce A. Chabner

    61. Cytotoxic Agents, Bruce A. Chabner, Joseph Bertino, James Cleary, Taylor Ortiz, Andrew Lane, Jeffrey G. Supko, and David Ryan

    62. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines, Bruce A. Chabner, Jeffrey Barnes, Joel Neal, Erin Olson, Hamza Mujagic, Lecia Sequist, Wynham Wilson, Dan L. Longo, Constantine Mitsiades, and Paul Richardson

    63. Natural Products in Cancer Chemotherapy: Hormones and Related Agents, Beverly Moy, Paul Goss, Richard J. Lee, and Matthew Smith


    64. Ocular Pharmacology, Jeffrey D. Henderer and Christopher J. Rapuano

    65. Dermatological Pharmacology, Craig Burkhart, Dean Morrell, and Lowell Goldsmith

    66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders, Bernard P. Schimmer and Keith L. Parker

    67. Environmental Toxicology: Carcinogens and Heavy Metals, Michael C. Byrns and Trevor M. Penning


    I. Principles of Prescription Order Writing and Patient Compliance, Iain L.O. Buxton

    II. Design and Optimization of Dosage Regimens: Pharmacokinetic Data, Kenneth E. Thummel, Danny D. Shen, and Nina Isoherranen


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    Goodman and Gilman's The Pharmacological Basis of Therapeutics 1 out of 5 based on 0 ratings. 1 reviews.
    baltoreader More than 1 year ago
    Why is the Nook version more expensive than the hardcover version? The Nook version can not be loaned, can not be sold back, can not be photocopied. I really liked the Nook sample, but the hardcover version is significantly cheaper AND I can sell it when I am done with it.