Heavy Metal Toxicity and Neurodegeneration

by Prasann Kumar PhD (Editor), PhD Gogia MS (Editor)

Overview

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease. - Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous system - Explains the mechanisms through which metals contribute to neurodegenerative diseases - Highlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Product Details

ISBN-13:	9780443365768
Publisher:	Elsevier Science & Technology Books
Publication date:	08/01/2025
Sold by:	Barnes & Noble
Format:	eBook
Pages:	400
File size:	64 MB
Note:	This product may take a few minutes to download.

About the Author

Dr. Prasann Kumar, assistant professor cum research intensive faculty in theDepartment of Agronomy, School of Agricultural (ICAR-Accredited), LovelyProfessional University, Punjab, specializes in stress physiology, plant tissue culture,physiology of plant?microbe/pathogen interaction, and biodiversity management.Dr. Kumar has completed the International Agricultural Rural DevelopmentProgramme from Cornell University, Ithaca, New York, United States. He hasreceived a doctorate from Banaras Hindu University, Varanasi. He also hasauthored 40 books published by national and international publishers, which finda place in national as well as various Overseas Institutions’ libraries. He hasguided 19 MSc students for their thesis.
Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University’s International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases.

Table of Contents

1. Biological Pathways of Heavy Metal Toxicity2. Mechanisms of Neurodegeneration Induced by Heavy Metals3. Lead Toxicity and Its Impact on Cognitive Function4. Mercury Poisoning: Effects on the Central Nervous System5. Arsenic Exposure and Neurotoxic Effects6. Cadmium and Its Role in Neurodegenerative Diseases7. Chromium Toxicity: Neurological Implications8. Interactions Between Heavy Metals and Neuroinflammatory Processes9. Oxidative Stress and Heavy Metal-Induced Neuronal Damage10. Genetic Susceptibility to Heavy Metal Toxicity11. The Role of Glutathione in Heavy Metal Detoxification12. Heavy Metals and Alzheimer's Disease: A Review13. Parkinson's Disease and Heavy Metal Exposure14. Multiple Sclerosis: The Impact of Heavy Metals15. Heavy Metals and Amyotrophic Lateral Sclerosis (ALS)16. Neurodevelopmental Disorders Linked to Heavy Metal Exposure17. Childhood Exposure to Heavy Metals and Long-Term Neurodevelopmental Effects18. Environmental Sources of Heavy Metals and Their Health Impacts19. Biomarkers for Assessing Heavy Metal Toxicity20. Diagnostic Techniques for Heavy Metal-Induced Neurotoxicity21. Prevention and Mitigation Strategies for Heavy Metal Exposure22. Therapeutic Approaches for Heavy Metal Detoxification23. Dietary Interventions for Reducing Heavy Metal Toxicity24. Pharmacological Treatments for Neurodegeneration Due to Heavy Metals25. Role of Chelation Therapy in Heavy Metal Detoxification26. Impact of Heavy Metals on Neuroplasticity27. Heavy Metal Toxicity and Psychiatric Disorders28. Epidemiological Studies on Heavy Metal Exposure and Neurodegeneration29. Regulatory Standards and Guidelines for Heavy Metal Exposure