Pub. Date:
Springer Berlin Heidelberg
Human Cytomegalovirus / Edition 1

Human Cytomegalovirus / Edition 1

by Thomas E. Shenk, Mark F. Stinski


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Product Details

ISBN-13: 9783540773481
Publisher: Springer Berlin Heidelberg
Publication date: 07/24/2008
Series: Current Topics in Microbiology and Immunology , #325
Edition description: 2008
Pages: 479
Product dimensions: 6.20(w) x 9.40(h) x 1.20(d)

Table of Contents

Forward.- 1. Human cytomegalovirus genome.- 2. Human cytomegalovirus microRNAs.- 3. Mutagenesis of the cytomegalovirus genome.- 4. Cytomegalovirus cell tropism.- 5. Cytomegalovirus entry and innate immune activation.- 6. Functions of human cytomegalovirus tegument proteins prior to immediate early gene.- expression.-7. Initiation of cytomegalovirus infection at ND10.- 8. Functional roles of the human cytomegalovirus essential IE86 protein.- 9. Nuts and bolts of human cytomegalovirus lytic DNA replication.- 10. Interactions of human cytomegalovirus proteins with the nuclear transport machinery.- 11. Structure and formation of the cytomegalovirus virion.- 12. Human cytomegalovirus modulation of signal transduction.- 13. Chemokines and chemokine receptors encoded by cytomegaloviruses.- 14. Subversion of cell cycle regulatory pathways by human cytomegalovirus.- 15. Modulation of host cell stress responses by human cytomegalovirus.- 16. Control of apoptosis by human cytomegalovirus.- 17. Aspects of human cytomegalovirus latency and reactivation.- 18. Murine model of cytomegalovirus latency and reactivation.- 19. Cytomegalovirus immune evasion.- 20. Cytomegalovirus vaccine development.- 21. Human cytomegalovirus infection in the developing placenta: maternal immunity and cytotrophoblast differentiation.- 22. Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing.- 23. Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease.-

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