Pub. Date:
Elsevier Health Sciences
Human Embryology and Developmental Biology / Edition 3

Human Embryology and Developmental Biology / Edition 3

by Bruce M. Carlson MD, PhD


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The completely revised and updated New Edition delivers comprehensive, clearly written coverage of the development of the human embryo from conception to birth. Using a classical morphological approach to embryology, it offers mechanistic explanations for both normal and abnormal human development, enabling readers to understand development in terms of cellular and molecular controls. And, a wealth of reader-friendly features make this resource exceptionally user friendly.

• Features an exceptionally reader-friendly format that includes Clinical Correlations boxes · Clinical Vignettes · timelines which highlight the progression of development · Key Molecules tables · and end-of-chapters summaries.
• Uses a wealth of full-color illustrations to provide a realistic representation of developmental concepts.

• Presents a new chapter that explores the fundamental aspects of molecular mechanisms in development, with coverage of important developmental molecules such as homeobox-containing genes · members of the transforming growth factor family · the fibroblast growth factor family · and the Pax genes.
• Includes new content on two developmentally important molecules: sonic hedgehog and retinoic acid.
• Offers updated material on left-ring asymmetry · major signaling centers in the early embryo · cross-sectional organization of the nervous system · the molecular organization of the gut · and the basis for the early establishment of the vascular system.

Product Details

ISBN-13: 9780323014878
Publisher: Elsevier Health Sciences
Publication date: 03/26/2004
Edition description: Older Edition
Pages: 512
Product dimensions: 8.50(w) x 10.88(h) x 0.93(d)

Table of Contents

Carnegie Stages of Early Human Embryonic Development (Weeks 1-8)

Major Developmental Events During the Fetal Period

Part I: Early Development and the Fetal-Maternal Relationship

Chapter 1:
Getting Ready for Pregnancy
Preparation of the Female Reproductive Tract For Pregnancy
Hormonal Interactions Involved with Reproduction in Males

Chapter 2:
Transport of Gametes and Fertilization
Ovulation and Egg and Sperm Transport

Chapter 3:
Cleavage and Implantation
Embryo Transport and Implantation

Chapter 4:
Molecular Basis for Embryonic Development
Fundamental Molecular Processes in Development

Chapter 5:
Formation of Germ Layers and Early Derivatives
Two-Germ-Layer Stage
Gastrulation and the Three Embryonic Germ Layers
Induction of the Nervous System
Cell Adhesion Molecules

Chapter 6:
Establishment of the Basic Embryonic Body Plan
Development of the Ectodermal Germ Layer
Development of the Mesodermal Germ Layer
Development of the Endodermal Germ Layer
Basic Structure of the 4-Week Old Embryo

Chapter 7:
Placenta and Extraembryonic Membranes
Extraembryonic Tissues
Chorion and Placenta
Placenta After Birth
Placenta and Membranes in Multiple Pregnancies

Chapter 8:
Developmental Disorders: Causes, Mechanisms, and Patterns
General Principles
Causes of Malformations
Developmental Disturbances Resulting in Malformations

Part II: Development of the Body Systems

Chapter 9:
Integumentary, Skeletal and Muscular Systems
Integumentary System
Muscular System

Chapter 10:
Limb Development
Initiation of Limb Development
Regulative Properties and Axial Determination
Outgrowth of the Limb Bud
Morphogenetic Control of Early Limb Development
Development of Limb Tissues

Chapter 11:
Nervous System
Establishment of the Nervous System
Early Shaping of the Nervous System
Histogenesis Within the Central Nervous System
Craniocaudal Pattern Formation and Segmentation
Peripheral Nervous System
Autonomic Nervous System
Later Structural Changes in the Central Nervous System
Ventricles, Meninges, and Cerebrospinal Fluid Formation
Cranial Nerves
Development of Neural Function

Chapter 12:
Neural Crest
Origins of the Neural Crest
Migrations of the Neural Crest
Differentiation of Neural Crest Cells
Major Divisions of the Neural Crest
Trunk Neural Crest
Circumpharyngeal Neural Crest
Cranial Neural Crest

Chapter 13:
Sense Organs

Chapter 14:
Head and Neck
Early Development of the Head and Neck
Fundamental Organization of the Pharyngeal Region
Development of the Facial Region
Development of the Pharynx and Its Derivatives

Chapter 15:
Digestive and Respiratory Systems and Body Cavities
Digestive System
Respiratory System
Body Cavities

Chapter 16:
Urogenital System
Urinary System
Genital System
Sexual Duct System
External Genitalia

Chapter 17:
Cardiovascular System
Developmental of the Vascular System
Developmental and Partitioning of the Heart
Initiation of Cardiac Function
Fetal Circulation

Chapter 18:
Fetal Period and Birth
Growth and Form of the Fetus
Fetal Physiology
Adaptations to Postnatal Life

Answers to Clinical Vignettes and Review Questions

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