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Hydrogen-Transfer Reactions / Edition 1

Hydrogen-Transfer Reactions / Edition 1


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Product Details

ISBN-13: 9783527307777
Publisher: Wiley
Publication date: 01/09/2007
Pages: 1603
Product dimensions: 7.28(w) x 10.24(h) x 4.33(d)

About the Author

Professor Schowen has closed his research groups, but continues to work in collaborations. Active programs include these projects:
- Studies of the mechanism, involvement of protein dynamics, and antiparasitic drug design for S-adenosylhomocysteine hydrolases
- Studies of the stability and degradation kinetics and mechanisms of peptide and protein pharmaceuticals in solution and in solid-phase, polymeric solids
- Design and characterization of green catalysts

Table of Contents

Prototropic rearrangements
Hydrogen transfer in the gas phase
Hydrogen transfer in liquids and solids
Hydrogen isotope effects and transition-state structure
Quantum theoretical treatments of hydrogen transfer
Principles of hydrogen transfer in solution
Multiple isotope effects as diagnostic tools of mechanism
NMR Methods in the study of hydrogen transfer
Hydrogen transfer in ice
Hydrogen bonding and hydrogen transfer
Hydrogen transfer in designed catalysts
Hydrogen-atom transfer in solution

Proton transfer in solution reactions
Theory of proton transfer in enzymic and model reactions
Model reactions for enzymic hydride transfer
Proton transfer in enzymic acid-base catalysis
Proton conduction in enzyme action
Hydrogen bonding and enzyme catalysis
Prototropic rearrangements in enzymic systems
Proton transfer in thiamin activation and other enzymic C-H fissions
Proton transfer and protein folding
Quantum tunneling in enzymic hydrogen transfer
Hydrogen-atom transfer in enzymic systems
Hydrogen transfer and protein stability

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