Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics

Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics

Paperback(Softcover reprint of the original 1st ed. 1991)

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Product Details

ISBN-13: 9781468459067
Publisher: Springer US
Publication date: 06/14/2012
Series: Advances in Experimental Medicine and Biology , #285
Edition description: Softcover reprint of the original 1st ed. 1991
Pages: 454
Product dimensions: 7.01(w) x 10.00(h) x 0.04(d)

Table of Contents

Cholesterol Metabolism.- Transcriptional Regulation of the Human Apolipoprotein Genes.- Mutations and Variants of Apolipoprotein B that Affect Plasma Cholesterol Levels.- Molecular Genetics of Familial Hypercholesterolemia.- Investigation of Structural Domains on Human Serum Low Density Lipoprotein and Apolipoprotein B100.- Implications of Thiolester Linked Fatty Acids in Apolipoprotein B.- Factors Regulating the Distribution of Cholesterol between LDL and HDL.- Regulation of Hepatic Lipase Expression by an Intermediate of the Cellular Cholesterol Biosynthetic Pathway.- Human Plasma Lecithin:Cholesterol Acyltransferase (LCAT). On the Role of Essential Carboxyl Groups in Catalysis.- Plasma Lipoprotein Phenotype in Response to Cholesteryl Ester Transfer Protein Levels in Dyslipoproteinemia.- HDL Receptor-mediated Cholesterol Efflux from Cells and its Regulation.- Binding of Apolipoproteins A to Adipose Cells: Role of Receptor Sites in Cholesterol Efflux and Purification of Binding Protein(S).- Lipoprotein A-I Containing Particles..- Distribution of Cholesterol within High Density Lipoproteins Fractionated by Immunoaffinity Chromatography.- Metabolic Role of Human Apopoprotein A-IV.- Regression of Atheroma and Putative Role of CETP in Cholesteryl Ester Removal.- Symmetry of the Surface, and Structure of the Central Core of Human LDL Particles, Analyzed by X-ray Small Angle Scattering.- Role of Amphipathic Helixes in HDL Structure/Function.- Conformational Properties of Apolipoproteins Studied by Computer Graphics.- Alterations of High Density Lipoproteins Induced by ThyroidHormones in Man and Rat 147.- The HELP-system in the Treatment of Severe Hypercholesterolaemia: Acute and Long-term Experience.- Familial Hypocholesterolemia and HDL Deficiency.- Mechanisms of Hypocholesterolemia.- Origin of Cholesterol and Bile Acids in the Diverted Bile of Two Patients with Total Small Bowel Resection.- In Vivo Kinetics.- Berman’s Simulation Analysis and Modeling.- Considerations in Designing and Analyzing Data from Apo-B Turnover Studies.- What Is Meant by Overproduction of Apo B-containing Lipoproteins?.- Kinetics of Heterogeneous Populations of Particles.- HDL Metabolism in HDL Deficiency Associated with Familial Hypertriglyceridemia: Effect of Treatment with Gemfibrozil.- Recent Advances in Lipoprotein Metabolism and the Genetic Dyslipoproteinemias.- Kinetic Studies of the Origin of Apolipoprotein (apo) B-100 in Low Density Lipoproteins of Normal and Watanabe Heritable Hyperlipemic (WHHL) Rabbits.- Alterations in Cholesterol Metabolism in the Genetically Hypercholesterolemic RICO Rat: An Overview.- Hypertriglyceridemia.- Genetic Variation at the Lipoprotein Lipase Gene Associates With Coronary Arteriosclerosis.- The Lipid Surface of Triglyceride-Rich Particles Can Modulate (Apo)Protein Binding and Tissue Uptake.- Structure and Metabolism of Low Density Lipoproteins from Normaland Hypertriglyceridemic Subjects 289.- The ApoB 100-apo(a) Complex: Relation to Triglyceride-Rich Particles.- ApoB-Containing Lipoprotein Particles as Risk Factors for Coronary Artery Disease.- In Vitro Binding and In Vivo Uptake of Chylomicron Remnants after their Hydrolysis by Hepatic Lipase.- The Endocytosis of Lipoproteins by the Liver and their Intracellular Pathway in Comparision to other Ligands.- Concomitant Inhibition of VLDL Triglyceride and Apoprotein Secretion by Hepatocytes of Rats Adapted to a High-fat Diet.- Molecular Genetics of ApoC-II and Lipoprotein Lipase Deficiency.- What Factors Regulate the Action of Lipoprotein Lipase?.- Pathogenesis of Atherosclerosis.- Cytotoxicity of Remnants of Triglyceride-Rich Lipoproteins: An Atherogenic Insult?.- The Role of Oxidized LDL in Atherosclerosis.- Probucol and its Mechanisms for Reducing Atherosclerosis.- Proteoglycans, Lipoproteins, and Atherosclerosis.- Immune Mechanisms in the Pathogenesis of Atherosclerosis.- Cholesterol Level in Circulating Immune Complexes as a Marker of Coronary Atherosclerosis.- Antibody-like Immunoglobins G against Low Density Lipoprotein that Stimulate Lipid Accumulation in Cultured Cells.- Nutritional Regulation of Apolipoprotein Genes: Effect of Dietary Carbohydrates and Fatty Acids.- Lipoprotein Structure and Metabolism During Progression and Regression of Atherosclerosis in Pigs Fed With Pish Oil-Derived Fatty Acids.- Contributors.

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