Imaging in Neurodegenerative Disorders

Imaging in Neurodegenerative Disorders

by Luca Saba

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Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Product Details

ISBN-13: 9780191651403
Publisher: OUP Oxford
Publication date: 01/08/2015
Sold by: Barnes & Noble
Format: NOOK Book
Pages: 640
File size: 48 MB
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About the Author

Luca Saba received the MD from the University of Cagliari, Italy in 2002. Today he works in the Azienda Ospedaliero Universitaria of Cagliari. Dr Saba research fields are focused on Multi-Detector-Row Computed Tomography, Magnetic Resonance, Ultrasound, Neuroradiology, and Diagnostic in Vascular Sciences. Dr. Saba has won 15 scientific and extracurricular awards during his career. He has presented more than 450 papers and posters in National and International Congress (RSNA, ESGAR, ECR, ISR, AOCR, AINR, JRS, SIRM, AINR). He wrote 18 book-chapters and he is Editor of 7 books in the field of Computed Tomography, Cardiovascular, Plastic Surgery, Gynecological Imaging and Neurodegenerative imaging. He is member of the Italian Society of Radiology (SIRM), European Society of Radiology (ESR), Radiological Society of North America (RSNA), American Roentgen Ray Society (ARRS) and European Society of Neuroradiology (ESNR) and serves as Reviewer of more than 30 scientific journals.

Table of Contents

Section 1: Introduction
1. Epidemiology of neurodegenerative diseases, Giancarlo Logroscino and Rosanna Tortelli
2. Metabolomics of neurodegenerative disorders, Luigi Barberini, Luca Saba, Claudia Fattuoni, Matteo Fraschini, and Francesco Marrosu
3. Transcriptome profiling in neurodegenerative disorders, James D Mills and Michael Janitz
4. Health economic considerations in neurodegenerative disorders, Thomas Rapp, Pauline Chauvin, Nadege Costa, and Laurent Molinier
5. Symptoms of neurodegenerative diseases, Robert Laforce, M. Lehmann, J. Macoir, S. Poulin, M. Roy, J.-P. Soucy, L. Verret, B. L. Miller, and R. W. Bouchard
Section 2: Imaging Technique
6. Computed Tomography, Michele Anzidei
7. General principles of Magnetic Resonance Imaging, Aart J. Nederveen, Matthan W.A. Caan, and Marion Smits
8. Nuclear medicine and radiology, Juergen Dukart and Bogdan Draganski
9. Molecular imaging and neurodegenerative diseases, Vivekanandan Palaninathan, Sivakumar Balasubramanian, D. Sakthi Kumar
10. PET imaging in neurodegenerative disorders - evolving techniques and new tracers, Christopher Kobylecki, Alexander Gerhard, and Karl Herholz
11. Radiopharmaceuticals for molecular imaging of neurodegenerative diseases, Shankar Vallabhajosula, Brigitte Vallabhajosula, and Lilja Solnes
Section 3: Neurodegeneration: Cognition
12. Neuroimaging of Alzheimer's disease, Charles D. Smith and Brian T. Gold
13. MRI-based imaging of Alzheimer's disease, F. Garaci, N. Toschi, T. Volpi, G. Gareffa, L. Spies, S.Lista, H. Hampel
14. Frontotemporal dementia, Jennifer L. Whitwell
15. Dementia with Lewy Bodies, Claire Henchcliffe and Thomas Tropea
16. Corticobasal Syndrome and Corticobasal Degeneration, Luke A Massey and Sean O'Sullivan
Section 4: Nueorregeneration: Movement
17. Parkinson's disease: Clinical and Imaging Features, Ana M. Franceschi, Sofia Pina, and Mauricio Castillo
18. Progressive Supranuclear Palsy (PSP), Dominic Paviour
19. Imaging in Huntington's disease, SJA van den Bogaard and RAC Roos
20. Multiple system atrophy, Keita Sakurai
Section 5: Neurodegeneration: Strength
21. Amyotrophic Lateral Sclerosis, Martin R. Turner
Section 6: Neurodegeneration: Coordination
22. Spinocerebellar Atrophies, Ana Solodkin, Gulin Oz, and Christopher M Gomez
23. Imaging in Neurodegenerative Disorder- Friedreich Ataxia, Hamed Akhlaghi, Martin B. Delatycki, Nellie Georgiou-Karistianis, and Gary F. Egan
24. Neuroimaging in human prion diseases, Damien Galanaud
Section 7: Neurodegeneration: PNS\ANS
25. Amyloidosis, Erez Nossek & Tali Jonas Kimchi
26. Metabolic and toxin related neurodegeneration, Amogh Hedge and CC Tchoyoson Lim
Section 8: Neurodegeneration: Myelin
27. Demyelinating diseases, Eytan Raz
28. Charcot-Marie-Tooth disease, Jose Berciano and Elena Gallardo
29. Neurodegenerative Disorders of the Basal Ganglia, Lev Bangiyev, Alexandra Roudenko, Eytan Raz, August Dietrich, Girish M. Fatterpekar
Section 9: Neurodegeneration: Trauma
30. Clinical benefit of dopamine transporter imaging in movement disorders and dementia, Jan Booij, Francoise J Siepel, Tirza C Buter, and Dag Aarsland
31. Neurodegeneration post trauma: Brain, Erin D. Bigler
32. Neurodegeneration post trauma: spine, J.A. Petersen, Spyros S. Kollias
33. Neurodegeneration post trauma: Peripheral nerves, Duan Xiao-Hui and Jun Shen
Section 10: Neuroimaging after therapy
34. Functional imaging of neurosurgery in Parkinson's disease, A.L. Bartels, R. Hilker
35. Neuroimaging after Cell-Based Therapy, Tsui A, Piccini P

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