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Immunobiology: The Immune System in Health and Disease is the current, authoritative introductory immunology textbook that leads the way into the 21st century. It is cutting-edge, definitive and lucid. Now in its Fourth Edition, Immunobiology has been used by over 100,000 undergraduates, post-graduates, medical students, and researchers. Immunobiology presents the field of immunology from the viewpoint of the host's response to infection.
NEW FEATURES AND UPDATES:
The new 'Signaling through Lymphocyte Receptors' chapter is a reorganization, clarification, and expansion of the B-cell and T-cell signaling information presented in the previous edition. It includes information on:
- newly understood cytokine signaling pathways.
- how signals 'switch off' some immunological pathways.
- cell death-regulating signaling pathways.
- how signaling maintains lymphocyte homeostasis.
- The 'Antigen Recognition by T Lymphocytes' chapter has been fully updated to include new information and illustrations such as the structural detail of TCR-MHC interactions. It also includes antigen processing by MHC class I and II, and how viruses interfere with these pathways.
- New information on cytokines and chemokines reflecting current research interests.
- Updates on transplant rejection including a new section on chronic organ rejection.
SPECIAL FEATURES OF PEDAGOGICAL VALUE:
- Easy to understand and assimilate full-color figures using distinct iconography, including new icons to illustrate signaling pathways such as cytoplasmic kinases and transcription factors.
- New user-friendly book style and easy to use sequential pagination.
- New-look cover.
- Fully up to date and informative CD antigen table.
- Cytokine summary table.
- Chemokine summary table.
- At-a-glance biographies of notable immunologists.
- Extensive glossary.
|Publisher:||Taylor & Francis|
|Edition description:||Older Edition|
|Product dimensions:||8.00(w) x 10.00(h) x 2.00(d)|
Table of Contents
|Part I||An Introduction to Immunobiology and Innate Immunity|
|Chapter 1||Basic Concepts in Immunology||1|
|Chapter 2||Innate Immunity||37|
|Part II||The Recognition of Antigen|
|Chapter 3||Antigen Recognition by B-cell and T-cell Receptors||103|
|Chapter 4||The Generation of Lymphocyte Antigen Receptors||135|
|Chapter 5||Antigen Presentation to T Lymphocytes||169|
|Part III||The Development of Mature Lymphocyte Receptor Repertoires|
|Chapter 6||Signaling Through Immune System Receptors||203|
|Chapter 7||The Development and Survival of Lymphocytes||241|
|Part IV||The Adaptive Immune Response|
|Chapter 8||T Cell-Mediated Immunity||319|
|Chapter 9||The Humoral Immune Response||367|
|Chapter 10||Adaptive Immunity to Infection||409|
|Part V||The Immune System in Health and Disease|
|Chapter 11||Failures of Host Defense Mechanisms||461|
|Chapter 12||Allergy and Hypersensitivity||517|
|Chapter 13||Autoimmunity and Transplantation||557|
|Chapter 14||Manipulation of the Immune Response||613|
|Part VI||The Origins of Immune Responses|
|Chapter 15||Evolution of the Innate Immune System||665|
|Appendix I||Immunologists' Toolbox||683|
|Appendix II||CD Antigens||731|
|Appendix III||Cytokines and their Receptors||747|
|Appendix IV||Chemokines and their Receptors||750|
|Appendix V||Immunological Constants||751|