Immunologic Disorders in Infants and Children / Edition 4

Immunologic Disorders in Infants and Children / Edition 4

by E. Richard Stiehm MD
Pub. Date:
Elsevier Health Sciences


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Immunologic Disorders in Infants and Children / Edition 4

Authored by scientists from the world's leading universities, the 4th Edition of this comprehensive reference incorporates important developments in pediatric immunology. The book is clearly organized into three detailed sections about the development and function of the immune system, immunodeficiency disorders, and immunologic aspects of pediatric illness. Chapters cover pediatric AIDS; dermatologic disorders; heart, lung, kidney, and pancreatic transplantation in pediatrics; important therapies and treatments; and much more!

Product Details

ISBN-13: 9780721649481
Publisher: Elsevier Health Sciences
Publication date: 01/01/1996
Edition description: Older Edition
Pages: 1084
Product dimensions: 8.50(w) x 11.00(h) x (d)

About the Author

MD, University of Wisconsin Medical School 1957

Affiliated at: Ronald Reagan UCLA Medical Center

Santa Monica-UCLA Medical Center and Orthopaedic Hospital

UCLA Children's Health Center

200 UCLA Medical Plaza Suite 265

Los Angeles, CA 90095


Clinical & Laboratory Immunology, American Board of Allergy and Immunology, 1986

Allergy & Immunology, American Board of Allergy and Immunology, 1974

Pediatrics, American Board of Pediatrics, 1964

Fellowship: Biochemistry, University of Wisconsin Hospitals and Clinics, 1958 - 1959

Residency, Immunology, Moffitt Hospital, 1963 - 1965, Pediatrics, Columbia Presbyterian Medical Center, 1961 - 1963


Rotating Intern, Philadelphia General Hospital, 1957 - 1958

Medical Degree

MD, University of Wisconsin Medical School, 1957

2009 Special Recognition Award from the American Academy of Allergy, Asthma and Immunology (AAAAI)

Dr. E. Richard Stiehm, professor of paediatrics in the division of allergy, immunology and rheumatology at Mattel Children's Hospital at the University of California at Los Angeles (UCLA), was presented with the 2007 Abbott Laboratories Award.

Table of Contents

Part IDevelopment and Function of the Immune System1
Chapter 1Ontogeny of Immunity3
Chapter 2The T-Lymphocyte System20
Chapter 3The B-Lymphocyte System: Fundamental Immunology53
Chapter 4The B-Lymphocyte System: Clinical Immunology85
Chapter 5The Polymorphonuclear Leukocyte System109
Chapter 6The Mononuclear Phagocytic, Dendritic Cell, and Natural Killer Cell Systems129
Chapter 7The Serum Complement System157
Chapter 8The Immune Response: Generation, Regulation, and Maintenance188
Chapter 9The Mucosal Defense System205
Chapter 10The Natural (Innate) Defense System245
Chapter 11The Immunology of Pregnancy273
Part IIPrimary Immunodeficiencies287
Chapter 12Immunodeficiency Disorders: General Considerations289
Chapter 13Antibody Deficiencies356
Chapter 14Selective IgA Deficiency427
Chapter 15Combined Immunodeficiencies447
Chapter 16Combined Immune Deficiencies Due to Purine Enzyme Defects480
Chapter 17Other Well-Defined Immunodeficiency Syndromes
Chapter 18Chromosomal Breakage Syndromes Associated with Immunodeficiency580
Chapter 19Autoimmune Lymphoproliferative Syndrome605
Chapter 20Phagocyte Disorders618
Chapter 21Deficiencies of the Complement System652
Part IIISecondary Immunodeficiencies685
Chapter 22The Physiologic Immunodeficiency of Immaturity687
Chapter 23Immune Responses in Malnutrition761
Chapter 24Genetic Disorders, Including Syndromic Immunodeficiencies785
Chapter 25Immune Deficiency in Metabolic Diseases820
Chapter 26Proliferative and Histiocytic Disorders835
Chapter 27Immunosuppression Induced by Therapeutic Agents and Environmental Conditions858
Chapter 28Immune Mechanisms in Infectious Disease871
Chapter 29Pediatric Human Immunodeficiency Virus Infection878
Chapter 30Stress-Related Immunodeficiencies: Trauma, Surgery, Anesthesia, Burns, Exercise, and Splenic Deficiencies952
Part IVImmunologic Aspects of Pediatric Illness965
Chapter 31Allergic Diseases967
Chapter 32Dermatologic Disorders988
Chapter 33Pulmonary Disorders1004
Chapter 34Gastroenterologic and Liver Disorders1055
Chapter 35Rheumatic Disorders1103
Chapter 36Periodic Fever Syndromes1171
Chapter 37Autoimmune Endocrinopathies1179
Chapter 38Immune-Mediated Renal Diseases1221
Chapter 39Immune-Mediated Hematologic and Oncologic Disorders1253
Chapter 40Immunologic Disorders of the Nervous System1282
Chapter 41Infection in the Compromised Host1310
Chapter 42Active and Passive Immunization in the Prevention of Infectious Diseases1360
Chapter 43Transplantation1400
Appendix 1Cluster Designation Nomenclature for Human Leukocyte Differentiation Antigens1449
Appendix 2Principal Human Cytokines and Chemokines1455

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