ISBN-10:
0123645816
ISBN-13:
9780123645814
Pub. Date:
10/01/1997
Publisher:
Elsevier Science
International Review Of Cytology / Edition 1

International Review Of Cytology / Edition 1

by Elsevier Science
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Product Details

ISBN-13: 9780123645814
Publisher: Elsevier Science
Publication date: 10/01/1997
Series: International Review of Cell and Molecular Biology Series
Pages: 308
Product dimensions: 0.81(w) x 6.00(h) x 9.00(d)

About the Author

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

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Presents current advances and reviews in cell biology, both plant and animal.

Table of Contents

Contributors vii

1 Cross-Talk Among Integrin, Cadherin, and Growth Factor Receptor: Roles of Nectin and Nectin-Like Molecule Hisakazu Ogita Yoshimi Takai 1

1 Introduction 2

2 Molecular and Structural Features of Nectin and Nectin-Like Molecule 4

3 Formation of Adherens Junctions Induced by the Nectin-Afadin System 9

4 Formation of Tight Junctions Regulated by the Nectin-Afadin System 22

5 Roles of Nectin and Necl-5 27

6 Common Utilization of Signaling Molecules in Forming Leading Edges and Cell-Cell Adhesion 39

7 Concluding Remarks 40

References 41

2 Neural Stem Cells in the Mammalian Brain A. V. Revishchin L. I. Korochkin V. E. Okhotin G. V. Pavlova 55

1 Introduction 56

2 Neural Stem Cells and Their Niches in the Adult Mammalian Brain 57

3 Transcriptional Regulation of NSC Self-Renewal and Differentiation 68

4 Neural Stem and Progenitor Cell-Based Therapy 82

5 Conclusions 90

Acknowledgments 91

References 91

3 Mechanisms of Mitotic Spindle Assembly and Function Claire E. Walczak Rebecca Heald 111

1 Introduction 112

2 Molecular Components of the Mitotic Spindle 113

3 Major Pathways of Spindle Assembly 119

4 Mechanisms of Chromosome Congression and Attachment 129

5 Mechanisms of Chromosome Segregation 138

6 Conclusions and Future Directions 143

Acknowledgments 144

References 144

4 Multiple Actions of Secretin in the Human Body Ian P. Y. Lam Francis K. Y. Siu Jessica Y. S. Chu Billy K. C. Chow 159

1 Introduction 160

2 Structure and Regulation of Secretion and the Gene 163

3 Secretin's Actions in the Gastrointestinal Tract 164

4 Secretin's Actions in Other Tissues 172

5 Summary and Future Prospects 178

References 179

5Biology of the Striated Muscle Dystrophin-Glycoprotein Complex James M. Ervasti Kevin J. Sonnemann 191

1 Introduction 192

2 Composition of the Core Dystrophin-Glycoprotein Complex 192

3 Function in Mammals 195

4 Function in Model Organisms 205

5 Concluding Remarks 207

Acknowledgments 208

References 208

6 Providing Unique Insight into Cell Biology via Atomic Force Microscopy Victor Shahin Nelson P. Barrera 227

1 Introduction 228

2 AFM: Principle of Operation and Operation Modes 229

3 AFM Can Measure Forces and Elasticity 232

4 Advantages of AFM 234

5 Application of AFM to Biology 235

6 Conclusions 246

Acknowledgments 247

References 247

7 Characteristics of Oxysterol Binding Proteins Daoguang Yan Vesa M. Olkkonen 253

1 Introduction 254

2 Subcellular Distribution of the ORPs 258

3 Role of the Mammalian ORPs in Lipid Metabolism 262

4 The Yeast S. cerevisiae ORPs 269

5 Role of ORPs in Cell Signaling 272

6 Future Perspectives 274

Acknowledgments 276

References 277

Index 287

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