ISBN-10:
0122386604
ISBN-13:
9780122386602
Pub. Date:
02/01/2000
Publisher:
Elsevier Science & Technology Books
Introduction to Biomedical Engineering / Edition 1

Introduction to Biomedical Engineering / Edition 1

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Overview

Introduction to Biomedical Engineering is intended to serve as an introduction to, and an overview of, the field of biomedical engineering. Over the past 50 years, as the discipline of biomedical engineering has evolved, it has become clear that it is a diverse, seemingly all-encompassing field, including such areas as biomechanics, biomaterials, bioinstrumentation medical imaging, rehabilitation, engineering, as well as biosensors, biotechnology, and tissue engineering. Although it is not possible to cover all of the biomedical engineering domains in this textbook, the authors have made an effort to focus on most of the major fields of activity in which biomedical engineers are engaged.

Chapters are written to provide historical perspective of the major developments in specific biomedical engineering domains, as well as the fundamental principles that underlie biomedical engineering design, analysis, and modeling procedures in those domains. Numerous examples, drill problems, and exercises are used to reinforce concepts and develop problem solving skills. In addition to the pedagogy within the book, the authors will maintain a Web site for relevant laboratory simulations and links to other biomedical engineering Web sites.

Product Details

ISBN-13: 9780122386602
Publisher: Elsevier Science & Technology Books
Publication date: 02/01/2000
Series: Biomedical Engineering
Edition description: Older Edition
Pages: 1062
Product dimensions: 7.76(w) x 9.49(h) x 2.08(d)

Table of Contents

FOREWORD xiii(2)
CONTRIBUTORS xv
1 BIOMEDICAL ENGINEERING: A HISTORICAL PERSPECTIVE
1(28)
1.1 Evolution of the Modern Health Care System
2(6)
1.2 The Modern Health Care System
8(9)
1.3 What Is Biomedical Engineering?
17(3)
1.4 Roles Played by Biomedical Engineers
20(3)
1.5 Professional Status of Biomedical Engineering
23(2)
1.6 Professional Societies
25(2)
Exercises
27(1)
Suggested Reading
28(1)
2 ANATOMY AND PHYSIOLOGY
29(50)
2.1 Introduction
30(2)
2.2 Cellular Organization
32(14)
2.3 Tissues
46(1)
2.4 Major Organ Systems
46(26)
2.5 Homeostasis
72(2)
Exercises
74(2)
Suggested Reading
76(3)
3 BIOELECTRIC PHENOMENA
79(60)
3.1 Introduction
80(1)
3.2 History
81(8)
3.3 Neurons
89(6)
3.4 Basic Biophysics Tools and Relationships
95(10)
3.5 Equivalent Circuit Model for the Cell Membrane
105(10)
3.6 Hodgkin--Huxley Model of the Action Potential
115(16)
Exercises
131(6)
Suggested Reading
137(2)
4 BIOMEDICAL SENSORS
139(40)
4.1 Introduction
140(2)
4.2 Biopotential Measurements
142(5)
4.3 Physical Measurements
147(14)
4.4 Blood Cases and pH Sensors
161(8)
4.5 Bioanalytical Sensors
169(2)
4.6 Optical Biosensors
171(5)
Exercises
176(1)
Suggested Reading
177(2)
5 BIOINSTRUMENTATION
179(54)
5.1 Introduction
180(4)
5.2 Basic Instrumentation System
184(2)
5.3 Analog Circuits
186(7)
5.4 Signal Conditioning
193(17)
5.5 Instrumentation Design
210(15)
5.6 Computer-Based Instrumentation Systems
225(2)
5.7 Summary
227(1)
Exercises
228(3)
Suggested Reading
231(2)
6 BIOSIGNAL PROCESSING
233(46)
6.1 Introduction
234(1)
6.2 Physiological Origins of Biosignals
234(4)
6.3 Characteristics of Biosignals
238(2)
6.4 Signal Acquisition
240(5)
6.5 Frequency Domain Representation of Biosignals
245(6)
6.6 The Z Transform
251(2)
6.7 Digital Filters
253(3)
6.8 Signal Averaging
256(4)
6.9 Wavelet Transform and Short-Time Fourier Transform
260(9)
6.10 Artificial Intelligence Techniques
269(7)
Exercises
276(1)
Suggested Reading
277(2)
7 PHYSIOLOGICAL MODELING
279(90)
7.1 Introduction
280(4)
7.2 An Overview of the Fast Eye Movement System
284(6)
7.3 Westheimer's Saccadic Eye Movement Model
290(6)
7.4 The Saccade Controller
296(4)
7.5 Development of an Oculomotor Muscle Model
300(12)
7.6 A Linear Muscle Model
312(6)
7.7 A Linear Homeomorphic Saccadic Eye Movement Model
318(6)
7.8 A Truer Linear Homeomorphic Saccadic Eye Movement Model
324(10)
7.9 Saccade Pathways
334(9)
7.10 System Identification
343(16)
Exercises
359(8)
Suggested Reading
367(2)
8 COMPARTMENTAL ANALYSIS
369(42)
8.1 Introduction
370(1)
8.2 Model Postulates
371(1)
8.3 Compartmental Structure
372(24)
8.4 Modified Compartmental Analysis
396(5)
8.5 Convective Transport between Physiologic Compartments
401(5)
Exercises
406(3)
Suggested Reading
409(2)
9 BIOMECHANICS
411(56)
9.1 Introduction
412(2)
9.2 Basic Mechanics
414(19)
9.3 Mechanics of Materials
433(7)
9.4 Viscoelastic Properties
440(5)
9.5 Cartilage, Ligament, Tendon, and Muscle
445(5)
9.6 Clinical Gait Analysis
450(13)
Exercises
463(1)
Suggested Reading
464(3)
10 CARDIOVASCULAR MECHANICS
467(70)
10.1 Introduction
468(1)
10.2 Definition of a Fluid and Basic Principles of Biofluid Mechanics
468(4)
10.3 Constitutive Modeling of Physiologic Fluids: Blood
472(18)
10.4 Generation of Flow in the Cardiovascular System: The Human Heart (Cardiology) and the Cardiac Cycle
490(10)
10.5 Fluid Dynamic Field Equations: Conservation of Mass, Energy, and Momentum
500(8)
10.6 Hemodynamics in Vascular Channels: Arterial (Time Dependent) and Venous (Steady)
508(20)
10.7 General Aspects of Control of Cardiovascular Function
528(2)
Exercises
530(5)
Suggested Reading
535(2)
11 BIOMATERIALS
537(42)
11.1 Introduction
538(1)
11.2 Mechanical Properties and Mechanical Testing
539(5)
11.3 General Classification of Materials Used in Medical Devices
544(10)
11.4 Degradation of Materials
554(5)
11.5 Biological Effects
559(9)
11.6 Impact of Degradation of Materials on the Biological System
568(1)
11.7 Biocompatibility Testing
569(2)
11.8 Biomaterials and Device Design Criteria
571(4)
Exercises
575(3)
Suggested Reading
578(1)
12 TISSUE ENGINEERING
579(78)
12.1 Cellular Therapies
581(8)
12.2 Tissue Dynamics
589(18)
12.3 Stem Cells
607(5)
12.4 The Cellular Fate Processes
612(10)
12.5 Cellular Communications
622(6)
12.6 The Tissue Microenvironment
628(11)
12.7 Scaling Up
639(5)
12.8 Delivering Cell Therapies in a Clinical Setting
644(4)
12.9 Conclusions
648(1)
12.10 Glossary
648(2)
Exercises
650(4)
Suggested Reading
654(3)
13 BIOTECHNOLOGY
657(40)
13.1 Introduction
658(10)
13.2 Basic Techniques
668(11)
13.3 Other Core Technologies
679(5)
13.4 Medical Applications
684(10)
Exercises
694(2)
Suggested Reading
696(1)
14 RADIATION IMAGING
697(48)
14.1 Introduction
698(1)
14.2 Emission Imaging Systems
699(17)
14.3 Instrumentation and Imaging Devices
716(5)
14.4 Radiographic Imaging Systems
721(21)
Exercises
742(1)
Suggested Reading
743(2)
15 ULTRASOUND
745(38)
15.1 Introduction
746(1)
15.2 Fundamentals of Acoustic Propagation
747(10)
15.3 Diagnostic Ultrasonic Imaging
757(14)
15.4 New Developments
771(9)
15.5 Biological Effects of Ultrasound
780(1)
15.6 Therapeutic Ultrasound
781(1)
Exercises
781(1)
Suggested Reading
782(1)
16 NUCLEAR MAGNETIC RESONANCE AND MAGNETIC RESONANCE IMAGING
783(60)
16.1 Introduction
784(3)
16.2 Nuclear Magnetism
787(6)
16.3 NMR
793(12)
16.4 MRI
805(23)
16.5 Instrumentation for MRI
828(11)
Exercises
839(2)
Suggested Reading
841(2)
17 BIOMEDICAL OPTICS AND LASERS
843(62)
17.1 Introduction
844(1)
17.2 Essential Optical Principles
845(5)
17.3 Fundamentals of Light Propagation in Biological Tissue
850(12)
17.4 Physical Interaction of Light and Physical Sensing
862(8)
17.5 Biochemical Measurement Techniques Using Light
870(8)
17.6 Fundamentals of Photothermal Therapeutic Effects of Lasers
878(10)
17.7 Fiber Optics and Waveguides in Medicine
888(7)
17.8 Biomedical Optical Imaging
895(5)
Exercises
900(3)
Suggested Reading
903(2)
18 REHABILITATION ENGINEERING AND ASSISTIVE TECHNOLOCY
905(38)
18.1 Introduction
906(6)
18.2 The Human Component
912(6)
18.3 Principles of Assistive Technology Assessment
918(3)
18.4 Principles of Rehabilitation Engineering
921(11)
18.5 Practice of Rehabilitation Engineering and Assistive Technology
932(4)
Exercises
936(5)
Suggested Reading
941(2)
19 CLINICAL ENGINEERING AND ELECTRICAL SAFETY
943(34)
19.1 Introduction
944(1)
19.2 A Historical Perspective
945(2)
19.3 The Role of the Clinical Engineer
947(5)
19.4 Safety in the Clinical Environment
952(2)
19.5 Electrical Safety
954(13)
19.6 Electrical Safety Programs
967(2)
19.7 The Future of Clinical Engineering
969(3)
19.8 Preparation for Clinical Engineers
972(1)
Exercises
973(2)
Suggested Reading
975(2)
20 MORAL AND ETHICAL ISSUES
977(32)
20.1 Introduction
978(1)
20.2 Morality and Ethics: A Definition of Terms
979(5)
20.3 Two Moral Norms: Beneficence and Nonmaleficence
984(1)
20.4 Redefining Death
985(4)
20.5 The Terminally Ill Patient and Euthanasia
989(4)
20.6 Taking Control
993(1)
20.7 Human Experimentation
993(1)
20.8 Definition and Purpose of Experimentation
994(1)
20.9 Informed Consent
995(5)
20.10 Regulation of Medical Device Innovation
1000(1)
20.11 Ethical Issues in Feasibility Studies
1001(2)
20.12 Ethical Issues in Emergency Use
1003(1)
20.13 Ethical Issues in Treatment Use
1004(1)
20.14 The Safe Medical Devices Act of 1990
1005(1)
Exercises
1006(1)
Suggested Reading
1007(2)
INDEX 1009

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