Journeys In Medicine And Research On Three Continents Over 50 Years

Journeys In Medicine And Research On Three Continents Over 50 Years

by Moyra Smith

Paperback

$38.00
View All Available Formats & Editions
Usually ships within 1 week

Overview

This book presents clinical and research aspects of medicine and social dimensions of healthcare. It is designed for an audience with interest in health and societal factors. It is in part autobiographical, based on different phases of the author's life in medicine over 50 years, who revisited cases and problems encountered as she worked in different countries, including South Africa, Scotland, England and North America. Essays encompass aspects of clinical medicine and aspects of research, particularly in Genetics and Genomic Medicine. New information on the topic or disorder and current opinions and approaches to finding solutions are reviewed.


Related collections and offers

Product Details

ISBN-13: 9789813209541
Publisher: World Scientific Publishing Company, Incorporated
Publication date: 08/23/2017
Pages: 356
Product dimensions: 6.00(w) x 8.90(h) x 0.60(d)

Table of Contents

Epigraph vii

Preface ix

Acknowledgements xv

Part I Social Dimensions of Health 1

1 Looking Back 3

2 Socio-economic Factors and Health: Medical School and Beyond 7

3 Trauma and Experiences in the Surgical Unit at Baragwanath 9

4 South Africa in the Past and in the Present Millennium 17

Part II Mothers and Children 21

5 Pregnancy and Hazards 23

6 Newborn Infants: Prematurity and Other Problems 29

7 Neural Tube Defects 35

8 Thyroid Hormone Deficiency in Infants and Children 41

Part III Infection Related Diseases 51

9 Fading, Emerging and Re-emerging Infectious Diseases 53

10 Tuberculosis 61

11 Tetanus 69

12 Viral infections that May Lead to Cancer 73

13 HIV/AIDS 81

Part IV Infections, Therapy and Prevention 87

14 The Golden Age of Antibiotics, and Has it Passed? 89

15 Antibiotic Resistance Mechanisms 95

16 Genomics and Natural Product Discovery 101

17 The Human Microbiome 105

18 Bacterial Microfilms 109

19 Strategies to Overcome the Problem of Bacterial Antibiotic Resistance 113

20 Point of Care Diagnostics 117

21 Defining Biomarkers to Help Distinguish Viral Diseases from Bacterial Diseases 119

22 Vaccines in the 21st Century 121

23 New Economic Approaches to Financing New Medications 127

Part V Nuclei, Chromosomes, Genomes and Gene Products 133

24 Entering Genetics through Studies on Nuclei, Chromatin and Chromosomes 135

25 Excursions into Enzymes, Polymorphisms and Biochemistry 141

26 Gene Mapping and Somatic Cell Genetics 149

27 Catching up on Developments in Molecular Genetics through the 1960s and 1970s 153

28 The Human Genome Project and Advances in Genetics and Genomics 163

29 Gene Regulation and "Endless Forms Most Beautiful" 177

Part VI Genetic Variation and Diseases 199

30 Founder Mutations, Specific Genetic Disorders in Different Countries 201

31 Hypercholesterolemia, Heart Disease and Atherosclerosis 203

32 Cardiomyopathy 207

33 Porphyria 211

34 Gaucher Disease 217

35 Hemoglobins and Hemoglobinopathies 219

36 Hemophilia 235

37 Cystic Fibrosis 241

38 Inborn Errors of Metabolism 249

Part VII Complexities and Striving for Insights 265

39 Evolution of Therapies, Complexities, Root Causes, and Moves Toward Personalized Medicine 267

40 Psychiatry 273

41 Aging 277

42 Neurodegenerative Diseases 285

Part VIII The Future 295

43 Stem Cells and Pluripotent Stem Cells 297

44 Gene Editing 305

45 Antisense Oligonucleotides 309

46 Towards the Future of Cancer Diagnosis and Therapy 311

47 Improved Health, Prolonged Survival and Wellness 323

48 Health: Human and Planetary 325

Index 337

Customer Reviews