Pub. Date:
Springer Netherlands
Lipid-mediated Protein Signaling

Lipid-mediated Protein Signaling

by Daniel G.S. CapellutoDaniel G.S. Capelluto


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This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.

Product Details

ISBN-13: 9789402407235
Publisher: Springer Netherlands
Publication date: 08/23/2016
Series: Advances in Experimental Medicine and Biology , #991
Edition description: Softcover reprint of the original 1st ed. 2013
Pages: 219
Product dimensions: 7.01(w) x 10.00(h) x (d)

Table of Contents


1. Sphingomyelin and its role in cellular signaling; Mahua Chakraborty and Xian-Cheng Jiang

2. The driving force of alpha-synuclein insertion and amyloid channel formation in the plasma membrane of neural cells: key role of ganglioside- and cholesterol-binding domains; Jacques Fantini and Nouara Yahi

3. The enigmatic role of sulfatides: new insights into cellular functions and mechanisms of protein recognition; Shuyan Xiao, Carla V. Finkielstein, and Daniel G. S. Capelluto

4. Phosphoinositides and PDZ Domain Scaffolds; Anna Maria Wawrzyniak, Rudra Kashyap and Pascale Zimmermann

5. PtdIns(4)P signalling and recognition systems; Marc Lenoir and Michael Overduin

6. PtdIns(4,5)P2-Mediated Cell Signaling: Emerging Principles and PTEN as a Paradigm for Regulatory Mechanism; Arne Gericke, Nicholas R. Leslie, Mathias Lösche, and Alonzo H. Ross

7. Role of Phosphatidylinositol 3,4,5-trisphosphate in Cell Signaling; Robert D Riehle, Sinziana Cornea and Alexei Degterev

8. The Role of Phosphoinositides and Inositol Phosphates in Plant Cell Signaling; Glenda E. Gillaspy

9. Phosphatidic Acid-Mediated Signaling; Yu Liu, Yuan Su, and Xuemin Wang

10. Phosphatidylserine-mediated cellular signaling; Jason G. Kay and Sergio Grinstein

11. Cardiolipin-mediated cellular signaling; Vinay A. Patil and Miriam L. Greenberg


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