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Product Details

ISBN-13: 9783527293834
Publisher: Wiley
Publication date: 05/07/1996
Series: Methods and Principles in Medicinal Chemistry Series , #4
Pages: 439
Product dimensions: 6.93(w) x 9.69(h) x 0.97(d)

Table of Contents

From the contents:
Lipophilicity: The empirical tool and the fundamental objective/
Lipophilicity: A history/
Thermodynamics of van der Waals and hydrophobic interactions/
Intramolecular interactions encoded in lipophilicity: their nature and significance/
Lipophilicity measurement by reversed-phase high performance liquid chromatography (RP-HPLC)/
Centrifugal partition chromatography for lipophilicity measurements/
Assessment of distribution - pH profiles/
Estimation of lipophilicty by reversed-phase thin layer chromatography/
The future of log P calculation/
Theoretical calculation of partition coefficients/
Cellular automata model of partitioning between liquid phases

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