Mechanisms of Protein Synthesis: Structure-Function Relations, Control Mechanisms, and Evolutionary Aspects

Mechanisms of Protein Synthesis: Structure-Function Relations, Control Mechanisms, and Evolutionary Aspects

by E. Bermek (Editor)

Paperback(Softcover reprint of the original 1st ed. 1985)

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Product Details

ISBN-13: 9783642699146
Publisher: Springer Berlin Heidelberg
Publication date: 12/06/2011
Series: Proceedings in Life Sciences
Edition description: Softcover reprint of the original 1st ed. 1985
Pages: 222
Product dimensions: 6.69(w) x 9.61(h) x 0.02(d)

Table of Contents

Ribosome Structure.- RNA Structure, Free and on the Ribosome, as Revealed by Chemical and Enzymatic Studies.- Studies of E. coli Ribosomes Involving Fluorescence Techniques.- Ribosomal Components of the Peptidyl Transferase Center.- Elongation Factor Tu Interactions.- Interaction Between Elongation Factor Tu and Aminoacyl-tRNA.- Recognition of Aminoacyl-tRNA by Bacterial Elongation Factor Tu.- Transfer RNA Binding to Ribosomes.- tRNA Binding to and Topographical Arrangement on E. coli Ribosomes.- Ribosomal Translocation.- Studies on Structural Dynamics of the Translating Ribosome.- Proof-Reading in Translation.- The Effect of “In Vivo” Incorporation of ?-Aminobutyric Acid into E. coli Proteins.- Regulation of Eukaryotic Chain Initiation.- A Direct Correlation Between the Affinity of a Given mRNA for Eukaryotic Initiation Factor 2 and its Ability to Compete in Translation.- Regulation of Initiation Factor Activity.- Translational Control of Protein Synthesis in Reticulocyte Lysates by eIF-2? Kinases.- Calcium Ions and Phospholipid Activate a Translational Inhibitor in Reticulocyte Lysates.- High pO2 -Promoted Activation of a Translational Inhibitor in Rabbit Reticulocytes: Role of the Oxidation State of Sulfhydryl Groups.- Eukaryotic Chain Elongation.- Guanine Nucleotide Binding to Eukaryotic Elongation Factor 2: A Possible Control Mechanism of Eukaryotic Chain Elongation.- Evolution and Selective Action of Translational Inhibitors.- Some Interesting Features of a Halobacterial Gene and its mRNA.- Cell Evolution and the Selective Action of Translation Inhibitors.- Concluding Remarks.

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