This book represents the proceedings of a Satellite Symposium of the XIth International Congress of Biochemistry on "Control of Membrane Fluidity" which was held on July 7, 1979 at the Charles H. Best Institute, University of Toronto, Toronto, Canada. The meeting was organized by M. Kates and A. Kuksis and was supported by the International Congress of Biochemistry. The purpose of the meeting was to review recent progress in many different areas of investigation bearing on the role of lipids in the structural and functional property of the cell membrane commonly referred to as fluidity. The aim was to emphasize the factors controlling membrane fluidity as studied in appropriate in vitro and in vivo experiments. The Symposium included invited review papers and short papers offered by discussants. In assem· bling the book no distinction has been made between the two types of presentations, nor has any significance been attached to the chronological order of their presentation in the Symposium. As a result it was possible to provide a much more coherent and continuous presentation than that available at the meeting.
Table of ContentsI Measurement of Membrane Lipid Composition and Fluidity.- New Approaches to Lipid Analyses of Lipoproteins and Cell Membranes.- Determination of Molecular Species of Glycerophospholipids by a GC-MS Selected Ion Monitoring Technique.- High-Precision TLC-Densitometry of Membrane Lipids.- The Pulmonary Surfactant: Control of Fluidity at the Air-Liquid Interface.- Fluidity of Membrane Lipids.- II Correlation of Membrane Fluidity with Physiological Activity.- Adaptive Regulation of Membrane Lipid Biosynthesis in Bacilli by Environmental Temperature.- Activity of Membrane-Bound Enzymes (Respiratory Chain) During Adaptation of Fish to Temperature Changes.- Effect of Membrane Lipid Composition on Mobility of Lymphocyte Surface Immunoglobulins.- Plasma Mebrane Mg2+ATPase Activity is Inversely Related to Lipid Fluidity.- Alkaline Phosphatase in Red Cell Membrane: Interconnection of Activities and Membrane Lipid Fluidity.- Membrane Permeability in Porcine Malignant Hyperthermia.- III Fatty Acid Changes Accompanying Physiological Events.- Role of Phospholipid Desaturase in Control of Membrane Fluidity.- Membrane Fluidity and the Activity of Bovine Brain Phospholipid Exchange Protein.- The Regulation of Bacterial Membrane Fluidity by Modification of Phospholipid Fatty Acyl Chain Length.- The Question of Membrane Fluidity in an Anaerobic General Fatty Acid Auxotroph.- Thermal Control of Fatty Acid Synthetase from Brevibacterium ammoniagenes.- Why Do Prokaryotes Regulate Membrane Fluidity?.- Docosahexaenoyl Chains Are Introduced into Phosphatidic Acid During de novo Synthesis in Retinal Microsomes.- IV Phospholipid Changes Accompanying Physiological Events.- Dynamics of Membrane Fatty Acids During Lymphocyte Stimulation by Mitogens.- Phosphatidylinositol as a Source of Diacylglycerol to Promote Membrane Fusion in Exocytosis.- Glycosphingolipid Domain Formation and Lymphoid Cell Activation.- Phospholipid Metabolism of Rat Gastric Mucosa.- Effect of Temperature on the Biosynthesis of 3-sn-Phosphatidylcholine by Fusarium oxysporum F. sp. Lycopersici.- In vivo Modification of Phospholipid Polar Head Groups and Alterations in Membrane Activities and Cellular Events.- V Homeostatic Regulation of Membrane Fluidity.- Homeostatic Control of Membrane Lipid Fluidity in Fusarium.- Homeoviscous Adaptation in Psychrophilic, Mesophilic, and Thermophilic Yeasts.- Regulation of Membrane Fluidity in Anaerobic Bacteria.- Regulation of Membrane Fluidity During Temperature Acclimation by Tetrahymena pyriformis.- Modification of Lipid Composition and Mebrane Fluidity in Tetrahymena.- Regulation of Phospholipid N-Methylation in the Hepatocyte.- Author Index.